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Cadidroxyl 500 is manufactured and registered by US Pharma USA Co., Ltd. Let's learn more about the use of Cadidroxyl 500 through the article below.
1. What is Cadidroxyl 500?
Cadidroxyl 500 medicine has the main ingredient containing the active ingredient Cefadroxil (as Cefadroxil monohydrate) with a content of 500mg. The drug is prepared in the form of hard capsules, packed in a bottle of 100 capsules and a box of 10 blisters x 10 capsules / 1 blister.
2. Effects of the drug Cadidroxyl 500
Cadidroxyl 500 has the following effects:
Cefadroxil is effective against gram-positive bacteria such as staphylococcus, pneumococcus, streptococcus (except Methicillin-resistant streptococcus), active ingredient Cefadroxil has a medium spectrum of activity. In addition, the drug is also effective on some gram-negative bacteria such as Klebsiella pneumoniae, E. coli, Shigella and Proteus mirabilis. Mechanism of action of active ingredient Cefadroxil: Inhibits the synthesis of bacterial cell wall and the final stage of bacterial cell wall synthesis, bacteria will be destroyed without a protective wall. There are strains resistant to Cefadroxil such as: Proteus with positive indole reaction, methicillin-resistant Staphylococcus, Enterococcus, Pseudomonas aeruginosa, Enterobacter, Bacteroides. With the above mechanism of action, Cadidroxyl 500 is indicated for use in the following cases:
Treatment of acute, chronic or recurrent urinary tract infections: cystitis, acute pyelonephritis and chronic, urethritis. Treatment in respiratory tract infections: pharyngitis, tonsillitis, lobar pneumonia, bronchopneumonia, lung abscess, acute and chronic bronchitis, pleurisy, empyema, otitis media, laryngitis . Treatment in skin and soft tissue infections: abscesses, cellulitis, lymphadenitis, ulcers. Treatment of patients with infectious arthritis and osteomyelitis. Cadidroxyl 500 is not contraindicated in the following cases:
Do not use Cadidroxyl 500 in patients with a history of hypersensitivity to Cephalosporin and Penicillin group antibiotics.
3. How to use and dose of Cadidroxyl 500
How to take Cadidroxyl 500:
Cadidroxyl 500 is produced in the form of capsules, patients should take the tablet whole with a full glass of water. The active ingredient Cefadroxil is acid stable. Although it is not dependent on meals, taking the drug during or immediately after meals can help relieve gastrointestinal symptoms. Dosage of Cadidroxyl 500 in adults:
In infections of the skin and skin structure: use from 1-2 times a day, with a concentration of 1 gram / day and use it for 10 days. Bone and joint infections and respiratory tract infections: In case of mild and moderate infections, 500mg twice daily is used. For severe infections, use twice a year, divided into 2 times a year, and use it for 7 to 10 days or more. Dosage of Cadidroxyl 500 in children:
Children > 6 years old: use a dose of 500mg, divided into 2 times/day. Children from 1 to 6 years old: 250mg dose, divided into 2 times/day. In patients with renal impairment and the elderly, a dose adjustment should be made as prescribed by the physician depending on the creatinine clearance to prevent accumulation of the drug in the body. The starting dose in adults is 1 gram and a maintenance dose of 500mg is used, the intervals between the two doses are as follows:
Creatinine clearance from 0 to 10ml/min: 36 hours. Creatinine clearance from 10-25ml/min: 24 hours. Creatinine clearance from 25 to 50 mg/min: 12 hours. Treatment of overdose:
When using Cadidroxyl 500 drug overdose, patients may experience acute symptoms such as vomiting, nausea, diarrhea, in addition, neuromuscular hypersensitivity, convulsions may occur. , especially in patients with renal failure. It is recommended that patients when using an overdose should immediately report to the doctor and take the patient to the medical center for timely treatment.
4. Undesirable effects of the drug Cadidroxyl 500
During the use of the drug, the patient may experience the following undesirable effects: abdominal pain, vomiting, nausea, diarrhea, pseudomembranous conjunctivitis, digestive disorders, hepatitis, increased enzymes liver , restlessness, headache, dizziness, urticaria, rash, pruritus. Other possible side effects include vaginitis, genital itching, and transient neutropenia. Usually the side effects will disappear when the patient stops using the drug, however, it is recommended that patients experience unusual symptoms to notify the doctor for timely treatment instructions.
5. Drug interactions
Cadidroxyl 500 will be slowed down intestinal absorption when combined with Cholestyramine. Probenecid may decrease the excretion of Cadidroxyl 500, resulting in increased serum concentrations of Cefadroxil. When Cadidroxyl 500 is combined with Aminoglycosides and Furocemide can lead to a synergistic increase in nephrotoxicity. False-positive results may be obtained for the urine glucose test with reducing agents.
6. Use Cadidroxyl 500 . with caution
For patients with a history of hypersensitivity to penicillin group antibiotics, patients with renal failure or diseases of the gastrointestinal tract (especially colitis) should be cautious when using Cadidroxyl 500. The use of Cadidroxyl 500 for a long time may lead to overgrowth of non-susceptible strains, when superinfection is detected, it is necessary to stop using the drug immediately. Do not use for pregnant women and lactating women, if necessary, weigh the benefits and harms when using. Care should be taken when administering Cadidroxyl 500 to neonates and premature infants. The article provided information about the drug Cadidroxyl 500. To ensure safety for health and maximize the effectiveness of treatment, you need to use Cadidroxyl 500 exactly as directed by your doctor, store the medicine in a cool, dry place, avoid direct exposure to light. Sun, suitable temperature from 25 to 30oC.
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