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Betagine drug belongs to the group of vitamins and minerals, used in the treatment of vitamin B1, B6, B12 deficiency. Let's learn about Betagine drug information through the article below.
1. What is Betagine?
Betagine drug is made in capsule form, is a combination of 3 B vitamins including B1, B6 and B12, with the content of Vitamin B1 (Thiamin nitrate) 125mg, Vitamin B6 (Pyridoxine hydrochloride) 125mg, Vitamin B12 ( Cyanocobalamin) 125μg with other excipients such as magnesium stearate, tapioca starch just enough for 1 capsule. In which:
The need for vitamin B1 is directly related to the amount of carbohydrates provided and the body's metabolic rate. Vitamin B1 deficiency will cause beriberi edema, which manifests on the nervous system as peripheral neuritis, sensory disturbances in the extremities, cardiovascular symptoms such as dyspnea on exertion, palpitations, and palpitations. Tachycardia and other disturbances are demonstrated by electrocardiographic changes and by high-output heart failure. Vitamin B6 participates in the synthesis of Hemoglobin and gamma-aminobutyric acid (GABA) in the central nervous system. B6 deficiency can be caused by malabsorption (alcohol abuse, intestinal disease, burns, infections) or by drugs (isoniazid, cycloserin), thereby leading to iron deficiency anemia, peripheral neuritis. . Vitamin B12 plays an important role in the production of blood cells. Vitamin B12 deficiency can cause megaloblastic anemia, in addition to nerve damage by demyelination.
2. Uses of the drug Betagine
Betagine drug is used in the treatment of vitamin B1, B6, B12 deficiency such as:
Painful conditions caused by rheumatic or neurological causes. Weakness, fatigue, loss of appetite, anemia or convalescence. Do not use Betagine in the following cases:
Allergy to any ingredient in the drug. People with tumors, malignant tumors. Pregnant women and those who are breastfeeding.
3. Dosage and how to use Betagine
Drugs for oral use, dosage depends on each subject:
Adults: take 1-2 tablets/time x 2 times/day. Children: Take the dose as directed by your doctor.
4. Betagine side effects
When using Betagine medicine may cause some of the following side effects:
Related to Vitamin B1 (rare): anaphylactic shock, increased blood pressure, itching, urticaria, difficulty breathing, sweating... Related to Vitamin B6: severe peripheral neuropathy (this condition is reversible upon discontinuation of the drug); skin rash, itching, urticaria,... Related to vitamin B12 (rare): skin itching, erythema, urticaria, fever, headache, dizziness, nausea... During the use of the drug , if you see any serious abnormal symptoms, you should immediately call your doctor or medical staff for guidance and timely treatment.
5. Interaction with the drug Betagine
Vitamin B6 interacts with the following drugs:
Vitamin B6 reduces the therapeutic effect of Levodopa in Parkinson's disease Taking a dose of 200 mg/day can cause a 40-50% decrease in plasma concentrations of phenytoin and phenobarbital in patients. Vitamin B6 reduces manifestations of depression in women taking oral contraceptives. The need for Vitamin B6 is increased when used in combination with Hydralazine, isoniazid, penicillamine and oral contraceptives. Vitamin B12 interacts with the following drugs:
Vitamin B12 is reduced absorption when used with drugs Neomycin, aminosalicylic acid, antihistamines H2 and colchicine. Chloramphenicol reduces the anti-anemic effect of Vitamin B12.
6. Signs and treatment of an overdose of Betagine
Excessive use of Vitamin B6 (>= 2g/day) and prolonged (> 30 days) can cause neurosensory syndromes, loss of coordination, manifested as loss of spatial awareness, tremors limb head. Touch, which distinguishes between pain and heat, is less affected, and does not cause muscle weakness. Treatment: Stop taking the drug, it can be stopped for up to 6 months so that the sensory nervous system gradually returns to normal.
7. Notes and cautions when using Betagine
When using Betagine, caution should be exercised in the following cases:
Be careful with people with a history of atopic allergies (asthma, eczema). Not for use by pregnant and lactating women. The drug does not affect the ability to drive and use machines. Above is some information about the use of Betagine, if you need advice or have any questions, please consult a qualified doctor / pharmacist for guidance.
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