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Benzphetamine belongs to the group of drugs that stimulate the sympathetic nervous system and is manufactured in tablets with the strength of 25mg and 50mg. Benzphetamine is indicated for short-term reduction of appetite and is used in adjuvant therapy with appropriate weight loss diets and calorie restriction. However, Benzphetamine can cause some unwanted side effects. Therefore, before using Benzphetamine, patients need to carefully study the information and follow the doctor's instructions in treatment.
1. Mechanism of action of the drug Benzphetamine
Benzphetamine contains the ingredient benzphetamine hydrochloride - a sympathomimetic amine that has a mechanism of action similar to that of amphetamines, including central nervous system stimulation as well as an increase in blood pressure. When Benzphetamine is introduced into the body, there is a short-term tolerance and familiarity often occurs with this group of drugs.
Benzphetamine when entering the body is absorbed through the digestive system and gastric mucosa. Benzphetamine is 75 to 99% bound to plasma proteins. The drug is metabolized in the liver to form amphetamine and methamphetamine products. The drug has an extended half-life of 16 to 31 hours.
2. Indications and contraindications to the use of Benzphetamine
Benzphetamine is indicated to help reduce the appetite of people who are overweight and obese. Moreover, it also helps adjuvant treatment with more preferable weight loss diets. In addition, this product helps to limit calorie intake in obese people with a body mass index of 30kg/m2 or more.
However, Benzphetamine may be contraindicated in some cases of hypersensitivity to the active ingredient benzphetamine hydrochloride, or sympathomimetic amines or other components of Benzphetamine. And some cases have manifestations related to cardiovascular, arrhythmia, mild to moderate hypertension, hyperthyroidism, glaucoma glaucoma, agitation, pregnant women, patients with pre-existing medical conditions. abuse use and 12 year olds.
3. Dosage and usage of Benzphetamine
Dosage for Benzphetamine is indicated depending on the response level of the patient. The usual recommended starting dose ranges from 25 to 50 mg and is used 1 to 3 times a day, and this dose is increased over time as needed. Therefore, in some cases, patients can apply a starting dose of 25 to 30 mg with a frequency of once a day and then depending on the response, the dose will be increased accordingly.
Benzphetamine is likely to be most effective when used only once a day, possibly mid-morning or afternoon. The duration of use may depend on the patient's eating habits. However, for patients with indications for prolonged use of Benzphetamine, it is recommended to limit taking the drug in the late afternoon. Because Benzphetamine can increase the risk of insomnia, affecting the quality of sleep at night.
Note: The above recommended therapeutic dose for Benzphetamine is for reference only. Therefore, before using Benzphetamine, patients need to be prescribed by a doctor.
If the patient has missed a dose of Benzphetamine, use the missed dose as soon as he remembers. However, if the interval between the missed dose of Benzphetamine and the next dose is too close, skip the missed dose. Patients should not double the dose of Benzphetamine, because it can cause an overdose.
4. Unwanted side effects and some notes when using Benzphetamine
Benzphetamine can cause some unwanted side effects during treatment. However, with each case, Benzphetamine can occur in varying degrees from mild to severe. Some common side effects caused by Benzphetamine include: feeling restless, headache, dizziness, shaking, increased sweating, dry mouth, nausea, stomach pain, diarrhea...
However, In some cases, Benzphetamine can cause serious unwanted side effects with rare allergic reactions. These reactions may appear within minutes of taking Benzphetamine or may be longer within a few days. When serious side effects appear such as: shortness of breath, swelling, chest pain, pounding heartbeat, dangerously high blood pressure... the patient should stop using Benzphetamine and need medical help right away. instantly.
Although this is not a complete list of undesirable side effects of Benzphetamine, if the patient feels unusual signs during treatment, it is necessary to notify the doctor or medical staff immediately. .
A few notes when using Benzphetamine
Benzphetamine use should not be used in combination with other agents that cause anorexia including prescription drugs, over-the-counter drugs or herbs. Because it can increase the risk of severe pulmonary hypertension - pulmonary hypertension causes a rare disorder and increases the risk of death. Furthermore, pulmonary hypertension may also occur in patients receiving repeated treatment with Benzphetamine. During the course of treatment, if the patient feels symptoms or signs of severe progression with shortness of breath during strenuous activity, angina pectoris, edema, etc., the drug should be discontinued immediately and simultaneously. Time to check and evaluate the causes related to pulmonary hypertension. Patients should limit unwanted side effects as well as exposure to Benzphetamine. The problem of stimulant abuse in general and including Benzphetamine is quite common. Therefore, patients should be closely controlled when prescribed Benzphetamine. Because drug abuse can lead to severe psychological dependence and social dysfunction. Furthermore, the patient must not share his or her medication with others and must not use the medication that others share with him or her. For diabetic patients who are prescribed to use Benzphetamine, it is necessary to regularly check blood glucose levels so that the dose of Benzphetamine can be adjusted accordingly. Benzphetamine can impair kidney function, especially in the elderly. Therefore, in these patients, the signs of dizziness and hypertension are more common than in younger subjects. Benzphetamine may increase the risk of birth defects. Therefore, the drug is contraindicated for pregnant and lactating women. Hopefully, the above sharing will help the process of using and treating patients to achieve optimal results. It also minimizes possible side effects. If there are any questions, patients can talk directly with the prescribing doctor for in-depth advice.
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