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Aztor 10 is a drug used in the treatment of cholesterol-lowering support. So how is Aztor 10 used to be effective and safe for users? Let's find out in the article below.
1. What is Aztor 10?
Aztor 10 medicine has the main ingredient is atorvastatin calcium with the content of 10mg and the excipients are enough for 1 tablet. The drug is in the form of film-coated tablets. Box includes 5 small boxes, each box has 1 blister, each blister has 10 tablets.
2. Uses of Aztor 10
Aztor 10 is prescribed by doctors in the following cases:
Reduce total cholesterol, LDL-cholesterol, apolipoprotein and increase HDL-cholesterol in patients with primary hypercholesterolemia. Unresponsiveness to diet in patients with dysbetalipoproteinemia. The patient has a family history of homozygous familial hypercholesterolemia. Aztor 10 is contraindicated in the following cases:
Patients allergic to the main ingredient atorvastatin calcium or excipients in the drug. Patients with advanced liver disease or elevated liver enzymes more than 3 times the normal without an identifiable cause. Pregnant women and breastfeeding mothers.
3. Dosage and how to use Aztor 10
3.1. Dosage: Hypercholesterolemia and mixed dyslipidemia: The recommended starting dose is 10-20mg, taken once a day. Patients with high cholesterol, especially LDL cholesterol (over 45%). Need to reduce this index much should be used with a dose of 40mg, used once a day. The therapeutic dose range of the drug is 10-80mg/day. After 2-4 weeks of treatment, or when the dose is increased, the lipid index should be assessed to adjust the dose appropriately. Homozygous familial hypercholesterolemia: Use at a dose of 10-80mg/day. Combination therapy: Aztor 10 can be used in combination with resin to increase the effectiveness of treatment. Dosage depends on the doctor's prescription based on the test results on the patient. Dosage in renal impairment: Use the usual dose as recommended and no dose adjustment is required. 3.2. How to take the drug Aztor 10 can be used at any time of the day, regardless of the meal.
For effective use of Aztor 10, it is necessary to start with a diet and exercise regimen before starting drug treatment.
4. What to do when overdose, forget dose of Aztor 10?
Overdose: When a patient overdoses on Aztor 10, they should immediately notify a doctor or take them to the nearest medical facility for timely treatment support. However, there is no specific treatment for this condition, only treating the symptoms that occur and providing support to the patient. Hemodialysis does not increase the clearance of Aztor because of its high ability to bind to plasma proteins.
Missed dose: Take the missed dose of Aztor 10 as soon as you remember it. Skip the missed dose if it's already been another day and take your daily dose as directed by your doctor. Do not make up for a double dose. You should have a fixed schedule to take your medicine at the same time of day to avoid missing doses.
5. Side effects of drugs
Aztor 10 was well tolerated, and adverse events were usually mild and transient. There may be side effects when taking the drug such as: Constipation, bloating, indigestion, stomach pain, nausea, vomiting, headache and dizziness.
When experiencing side effects of Aztor 10, the patient should stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Rare side effects of Aztor 10 such as myalgia, myasthenia gravis, weakness, myositis, paresthesia, neuropathy, pancreatitis, hepatitis, anxiety, vomiting, hair loss, memory loss or loss , hyperglycemia, and increased HbA1C.
6. Aztor 10 . drug interactions
Co-administration of Aztor 10 with CYP3A4 inhibitors may increase plasma concentrations leading to an increased risk of myopathy and myopathy. When Aztor 10 is combined with amiodarone, the dose should not exceed 20 mg/day because of the increased risk of rhabdomyolysis. For effective treatment with doses above 20 mg/day, other statins may be used to limit this interaction (eg, pravastatin). Anticoagulants, indadione combined with Aztor 10 will increase bleeding time or prothrombin time. Therefore, prothrombin time should be monitored in patients receiving this combination. Concomitant administration of Aztor 10 with Digoxin increases the steady-state plasma concentration of digoxin by approximately 20%. Concomitant use of Aztor 10 with oral contraceptives containing norethsterone or ethicyl oestradiol will lead to an increase in plasma concentrations of these two substances.
7. Some notes when using Aztor 10
Before starting treatment with Aztor 10, care should be taken to rule out secondary causes of dyslipidemia and to check the lipid index on a monthly basis. During treatment, if creatine kinase is elevated, myositis occurs, or serum liver enzyme levels are 3 times higher than the upper limit of normal, the patient should reduce the dose or discontinue treatment. Patients need to see a doctor when they have muscle pain, muscle tension, muscle weakness, possibly accompanied by signs of fatigue and fever. Aztor 10 should be discontinued when there is a marked increase in CPK levels or if myopathy is diagnosed or suspected, with risk factors for the development of acute renal failure to paroxysmal myoglobinuria. Aztor 10 should be used with caution in patients with liver dysfunction and in patients with heavy alcohol consumption. Patients should have a reasonable diet before treatment with Aztor 10. At the same time, this reasonable diet should be maintained throughout the course of treatment with Aztor 10. The above is the important information of the patient. Aztor 10 drug. Reading carefully the instructions before using Aztor 10 and strictly following the doctor's instructions will bring the best treatment results for the patient.
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