This is an automatically translated article.
Asthasal HFA is a sympathomimetic, metered-dose spray for the treatment and prevention of bronchospasm. To understand more about the use, use and precautions when using the drug, please refer to the information below.
1. What are the uses of Asthasal HFA?
Asthasal HFA contains Salbutamol sulphate 100mcg/dose, made in the form of a metered dose inhaler with 200 doses per day.
Salbutamol has beta sympathomimetic effects, has effects on smooth and skeletal muscles, such as helping to dilate bronchi, relax the uterus. When the drug binds to beta-adrenergic receptors at the cell membrane, it causes the conversion of ATP to cyclic AMP, which activates protein kinase and ionized intracellular calcium, causing inhibition of actin-myosin binding, thereby causing smooth muscle relaxation.
This drug has selective beta 2 adrenergic receptor, anti-allergic effect by acting on mast cells, causing inhibition of the release of chemicals mediating bronchoconstriction such as histamine, chemotactic factors neutrophils and prostaglandin D2.
Beta 2 selective drugs can reduce the risk of side effects due to beta 1 hyperactivity.
2. Indications and contraindications of Asthasal HFA
Asthasal HFA is used in the following cases:
Reduces and prevents bronchospasm in patients with bronchial asthma, chronic bronchitis. Treatment of dyspnea, chronic obstructive pulmonary disease caused by emphysema. Prophylaxis of exercise-induced bronchospasm. Contraindications:
Patients with a history of allergic reactions to Salbutamol or excipients contained in the drug.
3. Dosage and how to use Asthasal HFA
How to use:
The drug is prepared as a metered dose inhaler, and the patient uses it by inhaling the solution through the respiratory tract. Read the instructions for use carefully to avoid overdosing or underdosing. How to use the drug you can refer to the following:
Using this medicine for the first time or using it again after you have stopped taking it, you need to spray it once into the air. Remove the cap of the mouthpiece and check that the mouthpiece is clean. Then shake the inhaler vigorously with your hand once. Hold the inhaler between your thumb and index finger. Breathe slowly through your mouth and then place the mouthpiece in your mouth between your teeth. Hold the mouthpiece firmly in your mouth with your lips. Tilt your head back, and begin to inhale slowly through your mouth. Simultaneously, use your thumb to press the inhaler to spray 1 dose, but you still maintain a state of rapid inhalation with the deepest possible breath. Remove the spray from your mouth. Hold your breath for at least 1 second and then slowly exhale. If a second dose is required, rest for at least 60 seconds and do the same as the first. Dosage:
The usual dose in the case of acute asthma prevention is 3 to 4 times a day, 2 doses each time. Treatment of acute asthma: Use 100 micrograms/dose for the patient, inhale 1-2 times through the mouth, 15 minutes later, if it doesn't help, you can inhale 1-2 more times. If relieved, maintenance treatment; did not improve, requiring hospitalization. Children treat acute asthma attacks and the dose is half that of adults. Prevention of exercise-induced asthma: Adults: Use an aerosol inhaler for 2 doses, 15 to 30 minutes before exercise; Children: Inhale 1 dose, 15 to 30 minutes before physical exertion. Overdose:
Possible symptoms of overdose are due to excessive beta-receptor stimulation, may include cramps, sore throat, increase or decrease in blood pressure, tachycardia, arrhythmias. heart, irritability, headache, tremor, dry mouth, nervousness, nausea, feeling dizzy, weakness, irritability and insomnia. There may be hypokalemia. Treatment of overdose: Stop taking Salbutamol and treat symptomatically, monitor until the patient is stable.
4. Undesirable effects of Asthasal HFA
Side effects of this drug are minimized because the dosage form adopts new technology and Salbutamol is well tolerated, dangerous toxic effects are rare. Adverse reactions to Salbutamol are generally similar to those of other sympathomimetics, but with salbutamol the rate of cardiovascular reactions is lower due to beta 2 selectivity.
The most common side effect is irritability. shivering and trembling. Other less common reactions may include headache, tachycardia and palpitations, insomnia, cramps, nausea, weakness, dizziness. Rare side effects: Urticaria, angioedema, rash and oropharyngeal edema. In some patients, when taking salbutamol can cause cardiovascular changes (pulse, blood pressure, some other symptoms or changes in the electrocardiogram). In general, the majority of adverse events were transient and did not require discontinuation of treatment with salbutamol. But if the side effects persist or are severe, you should seek medical advice.
5. Some things to keep in mind when taking Asthasal HFA
Before taking the drug, tell your doctor about your history of allergies and medical conditions. Salbutamol should be used with caution in cardiovascular patients (especially coronary insufficiency, arrhythmias and hypertension); patients with seizures, hyperthyroidism or diabetes; for patients who sometimes have sympathomimetic-like reactions to amines. These patients should be closely monitored while taking the drug. A combination of diet, breathing exercises, and allergen avoidance should be combined to reduce the risk of developing an asthma attack. Pregnancy: Although there is currently no evidence of teratogenicity, if absolutely necessary, this drug should only be used during the first 3 months of pregnancy. The following stages should not be used. Lactation: It is not known whether the drug is excreted in human milk. Since the potential for tumorigenesis has been observed in animal studies, a decision must be made whether to discontinue nursing or discontinue the drug. Children: The safety and effectiveness of this medicine in children under 6 years of age have not been established. Should not be used for this object. Drug interactions: Do not use Salbutamol at the same time as other sympathomimetic drugs because it may cause increased cardiovascular toxicity; Caution should be exercised when administering to patients being treated with monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants because the effect of salbutamol on the vascular system may be impaired; Beta-blockers and salbutamol should not be used concurrently because they inhibit each other's effects. Asthasal HFA is a prescription drug that is used as directed by your doctor, you need to have regular visits to check the effects of the drug on your body and have appropriate therapy to control bronchospasm. Never self-medicate without a doctor's prescription.
