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Amikacin 500mg drug has the main active ingredient in the form of Amikacin sulfate which is a semi-synthetic antibiotic of the Aminoglycoside group, effective against respiratory, urinary, and gynecological infections,... However, this is a Prescription drugs should be used strictly according to the instructions of the doctor or pharmacist.
1. What is Amikacin 500mg?
Amikacin 500mg is a semi-synthetic antibiotic whose main ingredient is Amikacin (Amikacin Sulfate). The drug is in the form of a powder for injection. Therefore, patients need to consult a doctor, do not arbitrarily use someone else's prescription because it is similar to the name of the drug or similar active ingredient. Accordingly, the drug is prescribed and treated by the doctor in the following diseases:
Treatment of respiratory tract infections Treatment of intra-abdominal infections. Treatment of urinary tract infections caused by gram-negative bacteria. Treatment of gynecological diseases. Treatment of musculoskeletal infections. Treatment of skin and skin structure infections. Treatment in case of bacteremia. In some cases, your doctor may prescribe Amikacin 500mg to treat other conditions. Therefore, patients need to adhere to and strictly follow the doctor's instructions.
2. Dosage and how to use Amikacin 500mg
Dosage of Amikacin 500mg: Intramuscular injection / subcutaneous injection / Slow intravenous infusion / Spinal injection.
Adults and children: Dosage 15mg/kg/day divided into 2 times, 7.5mg/kg each time or divided into 3 times a day, each time 05mg/kg. Neonates: Dosage is 15mg/kg/day in combination with serum antibiotic concentration control. In case of severe uncomplicated urinary tract infections, the dose is 7.5mg/kg/day. In the following cases, patients can be injected once a day, at a dose of 15mg/kg/day: Patients under 65 years old, patients with normal kidney function, infections not caused by gram-positive bacteria,... Dosage should not exceed 15g / day Amikacin can be used for spinal injection at a dose of 0.5mg / kg / 48 hours / time, used 3-4 times after the infection is gone. For patients with impaired renal function, hemodialysis should be adjusted appropriately by a specialist, and regularly assessed to check serum levels and renal function. Reference dosage can be from 5 to 7.5mg/kg/day. Note: The dosage of Amikacin 500mg above is for reference only. Depending on your condition and medical history, the appropriate dose will be prescribed by the doctor. Therefore, patients need to strictly follow the instructions of the doctor, medical professional to ensure the effectiveness of treatment and avoid unwanted side effects.
3. How to take Amikacin 500mg
Do not inject Amikacin 500mg directly into the vein.
Intramuscular injection: Mix 1 ampoule of 4ml distilled water into the powdered Amikacin vial, then shake well to dissolve the drug completely.
Intravenous infusion: Use 0.9% sodium chloride solution or 5% dextrose solution 100-200ml mixed with 01 vial of Amikacin powder and slow intravenous infusion over a period of 30-60 minutes for adults and infusion for 1 - 2 hours. 2 hours with young children.
4. Contraindications of Amikacin 500mg
Contraindications of Amikacin 500mg drug in the following patients:
Patients with hypersensitivity to one or any ingredient of the drug. Amikacin 500mg should not be used in patients with myasthenia gravis. Not for use by pregnant and lactating women.
5. Side effects of Amikacin 500mg
When using Amikacin 500mg you may experience the following side effects:
Dizziness, nausea, loss of balance Hearing loss. Decreased renal function: increased creatinine. The side effects mentioned above may not be listed when using Amikacin 500mg. Therefore, in the process of using the drug, if you experience any side effects, the patient should immediately notify the medical staff for timely treatment.
6. Amikacin 500mg . drug interactions
Currently, there have not been many studies on drug interactions of Amikacin 500mg with other drugs or foods. Therefore, to ensure patient safety, you should inform your doctor about your medical history, allergy history, drugs you are using, herbs, functional foods, herbal medicines, .. ...so that the doctor has appropriate considerations in treatment.
7. Overdose, missed dose and how to handle it
When used in excess, there is a risk of kidney toxicity, deafness and neurotoxicity such as muscle paralysis or difficulty breathing. In this case, hemodialysis will be required to help remove the amikacin from the blood.
When you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. You need to consult a professional doctor to get the best remedy.
Above is some information about the use of Amikacin 500mg, if you need advice or have any questions, please consult a qualified doctor/pharmacist for answers.
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