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Aldezil belongs to the group of antibacterial drugs, which are preferred for antibacterial, antiprotozoal, Trichomonas infections and vaginitis. To ensure the effectiveness of use when using Aldezil, users need to follow the instructions of their doctors, and refer to the following article for more information about the uses of Aldezil.
1. What are the effects of Aldezil?
1.1. What is Aldezil? Aldezil is an anti-infective, anti-viral and anti-fungal anti-parasitic drug - Drug Visa Number/ Registration Number/ Registration Number is: VN-0722-06 manufactured by Albert David., Ltd - India.
Aldezil drug contains the ingredient Metronidazole and is packaged in the form of Solution for infusion-0.5g/100ml.
1.2. What diseases does Aldezil treat? Following intravenous infusion, Metronidazole is rapidly distributed throughout the body's tissues and organs, including, bile, breast milk, synovial fluid and saliva.
Drug concentrations in serum and in cells are approximately the same. The drug concentration in the cerebrospinal fluid is approximately 60-100% of the drug concentration in the serum. Aldezil is indicated in the treatment of serious infections caused by susceptible anaerobes and protozoa such as: Intra-abdominal infections, gynecological infections, central nervous system infections, and central nervous system infections. skin and skin structures, sepsis and endocarditis.
Bacterial strains and protozoa that are very sensitive to metronidazole include: Bacteroides, Clostridia, Fusobacteria, Eubacteria, Anaerobic Cocci and Gardnerella vaginalis. In addition, Metronidazole is also active against Trichomonas vaginalis, Entamoeba histolytica, Giardia lamblia and Balantidium coli species. Metronidazole injection is effective in Bacteroides fragilis infections resistant to clindamycin, chloramphenicol and penicillin.
Aldezil is also used to prevent infection in patients undergoing colorectal surgery and gynecological surgery.
2. Usage of Aldezil
2.1. How to take Aldezil Aldezil can be given by slow intravenous infusion and by continuous or intermittent drip intravenous infusion.
2.2. Dosage of Aldezil Aldezil dosage:
Trichomoniasis: 2g or 1 course of treatment for about 7 days including 1 tablet x 3 times/day. Non-specific vaginitis: 2 tablets x 2 times/day. Simultaneous treatment of the patient's sexual partner is recommended. Amoeba diseases: Adults: 2-3 tablets x 3 times/day/for 5-10 days or 1.5-2.5g x 1 time/day, for 2-3 days. Children: 15mg/kg/day, divided into 3 times from 5 to 7 days. Diseases caused by dragon worms Dracunculus: Adults: 1 tablet x 3 times/day. Children: 25mg/kg/day, for 10 days. No more than 3 tablets/day (even if the child is over 30kg). Anaerobic infections are: 7.5mg/kg. 1g max. Prevention of postoperative anaerobic infections is: 20-30mg/kg/day, divided into 3 times. Gastrointestinal ulcers caused by H.pylori: 2 tablets x 3 times/day in combination with at least 1 other drug with H.Pylori-killing activity (such as bistmuth subsalicylate and amoxicillin). Handling missed dose:
Consult your doctor immediately before using the missed dose. Treatment of overdose:
There is no specific treatment for metronidazole overdose. However, the drug can be easily removed from plasma by hemodialysis.
3. Notes when using Aldezil
Patients taking metronidazole for more than 10 days should be monitored and treatment discontinued if signs of peripheral neuropathy or central neurotoxicity develop. The benefits of continuing treatment should also be weighed against the possible risks. Metronidazole should be used with caution in patients with a history of blood organ disorders. Metronidazole should be used with caution and reduced in dose and frequency in patients with severe hepatic impairment. No dose adjustment of metronidazole is required in renal impairment, nor is it necessary to change the dose in patients with renal impairment who have continuous peritoneal dialysis (IRD) or continuous peritoneal dialysis. desert. Metronidazole is removed during hemodialysis and therefore will need to be reintroduced immediately after hemodialysis. Metronidazole inhibits alcohol dehydrogenase and other alcohol oxidizing enzymes. The drug has mild disulfiram-type reactions such as hot flushes, headache, nausea, vomiting, abdominal cramps and sweating. Pregnancy: Metronidazole crosses the placental barrier fairly rapidly and will achieve a concentration ratio between placental stalk and maternal plasma of approximately 1. Although thousands of pregnant women have used the drug, it has not been observed. There are reports of teratogenicity. However, some studies have reported an increased risk of teratogenicity when the drug is used in the first 3 months of pregnancy. Therefore, it should not be used during early pregnancy and unless absolutely necessary. Lactation: Metronidazole will be excreted in breast milk fairly quickly, nursing infants may have plasma concentrations of the drug about 15% of the concentrations in the mother. Breastfeeding should be discontinued while being treated with metronidazole.
4. Aldezil side effects
Aldezil can lead to some unwanted side effects such as:
Common: Nausea, vomiting, loss of appetite, abdominal pain, diarrhea and an unpleasant metallic taste. Uncommon: Leukopenia. Rare: Blood: Agranulocytosis, seizures, peripheral polyneuropathy, headache, skin blistering, skin rash, itching and dark urine. If you experience these symptoms, the patient should stop using Aldezil and notify the doctor for appropriate treatment.
5. Aldezil drug interactions
Patients should not drink alcohol while taking Aldezil.
6. How to store Aldezil
The shelf life of Aldezil is 36 months from the date of manufacture. Aldezil medicine should be stored in a cool, dry place, at a temperature not exceeding 30°C, in the original packaging and must be protected from light and an acidic environment. Keep Aldezil out of reach of children. Above is all information about Aldezil drug, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Absolutely do not arbitrarily buy Aldezil treatment at home because there may be unwanted side effects.
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