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Agilermin drug has the main ingredients Phenylephrine HCl and Chlorpheniramine maleate, commonly used in the treatment of skin allergies, runny nose, stuffy nose,... Let's learn about the uses of Agilermin in the article below.1. What is Agilermin?
Agilermin is manufactured by Agimexpharm Pharmaceutical Joint Stock Company - Vietnam and circulated on the market with registration number VD - 13747-11. Agilermin is classified as an antiallergic drug and is used in cases of hypersensitivity. The main active ingredients of Agilermin are Phenylephrine HCl and Chlorpheniramine maleate.
Dosage form: Long film-coated tablets, each containing 5mg of Phenylephrine HCl, 4mg of Chlorpheniramine maleate and other excipients of the manufacturer.
Packing form: Bottle of 100 tablets.
2. What does Agilermin do?
Phenylephrine hydrochloride is an a1 (a1-adrenergic) sympathomimetic with direct effects on a1-adrenergic receptors causing vasoconstriction and hypertension, in which the effect of increasing blood pressure is weaker than that of norepinephrine but of duration. longer effect. Phenylephrine hydrochloride can slow the heart rate reflexively, reduce circulating blood volume, decrease blood flow through the kidneys, and reduce blood flow to other tissues and organs in the body.
At therapeutic doses, Phenylephrine hydrochloride does not stimulate the heart's b-adrenergic receptors (b1-adrenergic receptors), however, at high doses, it stimulates b-adrenergic receptors. At therapeutic doses, Phenylephrine hydrochloride has no effect on the central nervous system.
3. Indications and contraindications of Agilermin
Agilermin is usually indicated in the following cases:
Skin allergies such as eczema, urticaria,... Respiratory allergies such as runny nose, stuffy nose,... Contraindications: Absolutely do not use Agilermin in the following cases:
Hypersensitivity to any component of the drug Agilermin Acute bronchial asthma Topical topical use Prostate enlargement Narrow angle glaucoma Bladder neck obstruction Gastric ulcer Pyloric - duodenal obstruction Pregnant women Lactating women Infants and young children, premature babies.
4. Dosage and how to use Agilermin
To ensure the safety of using Agilermin, patients should only use it when prescribed by a doctor and must adhere to the treatment course, not to stop taking it, change the dosage and route of administration. . At the same time, do not share Agilermin with others or give it to others to use even if they have the same diagnosis.
Dosage:
Adults: 1 - 4 tablets (calculated as 4mg tablets of Chlorpheniramine) / time x 3 - 4 times / day. Children under 12 years old: 1/2 tablet/time x 2-3 times/day. How to use: Agilermin is prepared in the form of tablets and taken orally.
How to deal with a missed dose of Agilermin?
When you miss a dose, take another dose instead. If it is almost time for the next dose, skip the dose, do not increase the dose, or double the dose to make up for the missed dose. How to deal with an overdose of Agilermin?
The fatal dose of chlorpheniramine is 25-50mg/kg body weight. Overdose of Agilermin can cause sedation, paradoxical central nervous system stimulation, psychosis, apnea, seizures, convulsions, anticholinergic effects, dystonia, cardiovascular collapse, disturbances. rhythm. When detecting a patient with signs of overdose, it is necessary to quickly bring to the nearest emergency center for treatment. Family members are advised to bring all medications the patient has taken before to support the diagnosis. Treatment of Agilermin overdose consists of symptomatic and supportive treatment, with special attention to liver, kidney, cardiac, respiratory and water and electrolyte balance.
5. Undesirable effects
In addition to the therapeutic effect, the drug Agilermin may cause some unwanted effects during use such as drowsiness, lethargy, dizziness, ...
These are not all side effects of the drug. Agilermin, patients may experience other side effects that have not been reported or studied. Therefore, contact your doctor as soon as you have any unusual symptoms while using Agilermin.
6. Drug interactions
In order to use Agilermin safely and effectively, avoiding drug interactions, patients need to list and inform their doctors about all drugs being used to treat other diseases. At the same time, it is necessary to consult a doctor about the use of certain foods and drinks (such as alcohol, stimulants, fermented foods, ...) because drug-food interactions may occur. products during treatment with Agilermin.
Drugs that can interact with Agilermin such as:
Monoamine oxidase inhibitors: When combined with Agilermin, it prolongs and increases the anti-acetylcholine effect of Agilermin. Ethanol or hypnotic sedatives: May increase the CNS depressant effects of Agilermin when co-administered. Chlorpheniramine inhibits the metabolism of phenytoin and can lead to phenytoin toxicity. May obscure the signs of hearing caused by drugs such as aminosides Storage of medicines Store Agilermin in the original manufacturer's packaging, in a cool, clean place away from direct sunlight. , the temperature is below 30 degrees Celsius. Keep Agilermin out of reach of children as well as pets, avoid them not knowing how to chew may cause serious unwanted effects. Do not use Agilermin medicine that has expired or shows signs of change in color, properties, taste, no labels. Do not throw Agilermin into the toilet or plumbing unless told to do so.
