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Acepron 500 mg is a pain reliever and fever reducer used to treat a number of common health problems. The use of the drug needs to be in the right dose, avoiding overdose or forgetting the dose will cause unwanted side effects.
1. How does Acepron 500 mg work?
Acepron 500mg medicine contains the main ingredient Acetaminophen 500mg. This is an active ingredient in the group of non-steroidal anti-inflammatory drugs, non-steroidal anti-inflammatory drugs, salicylate-free, non-addictive to users. This active ingredient has the ability to increase the pain threshold for peripheral pain symptoms including headache, muscle pain, joint pain and unpleasant symptoms caused by colds and flu. Acetaminophen is the active metabolite of phenacetin, which acts on the thermoregulatory center in the hypothalamus to provide hypothermia and increased exothermic potential. Acepron contains Acetaminophen for its ability to dilate blood vessels and increase peripheral blood flow. From here, the drug helps reduce body temperature effectively in people with fever but has no effect on lowering body temperature in people with normal body temperature.
In addition, the drug does not work to treat inflammation, does not cause irritation or gastrointestinal bleeding, so it is often used as an alternative to Aspirin for patients who need pain relief and fever reduction.
Acepron 500 mg only affects the cyclooxygenase prostaglandin of the central nervous system, has no ability to act on systemic cyclooxygenase. As a result, the drug will not affect blood clotting ability and blood clotting time.
2. Indications and contraindications of Acepron 500 mg
2.1. Indications Acepron 500 mg drug has the main use of pain relief and fever reduction, is not addictive for users and is often used to treat the following health problems:People with headaches, dizziness . People with muscle pain, toothache, cold, fever, joint pain. Sometimes, medications are used to relieve pain and control symptoms of chronic arthritis when the disease is mild. 2.2. Contraindications Acepron 500 mg is contraindicated in the following cases:
People who are sensitive and allergic to the ingredient Acetaminophen in the drug. Patient has liver and kidney problems. People who have a history of alcoholism or are addicted to alcohol. Patients with cardiovascular disease. Patients with a history of anemia or a glucose-6-phosphate dehydrogenase deficiency.
3. Usage and dosage of Acepron 500 mg
Acepron 500 mg is used orally with reference doses as follows:
Adults and children over 12 years old: Use the drug at a dose of 500 - 1000 mg every 4-6 hours when needed, but not used more than 4g/day. Children from 6 to 12 years old: Use the drug at a dose of 250 - 500 mg every 4 - 6 hours as needed, up to 4 times a day. Patients absolutely do not use Acepron 500 mg for pain relief for more than 10 days for adults and more than 5 days for children. In addition, the drug is not suitable for reducing fever in cases where the fever is too high (above 39.5 degrees Celsius), the fever persists for more than 3 days, or the patient has recurrent fever.
4. Acepron 500 mg . side effects
Acepron 500 mg has few side effects, but when used for a long time in high doses, it can cause some problems such as:
Side effects on blood: Common include thrombocytopenia, leukopenia and pancytopenia bridge. Uncommon side effects: Skin rash, nausea, vomiting, hematopoietic disorders (neutropenia, pancytopenia, leukopenia), anemia. Long-term use of drugs can cause kidney disease, nephrotoxicity. Rare side effects: Hypersensitivity reactions include difficulty breathing, swelling of the face, swelling of the throat, swelling of the tongue. When these side effects appear, stop using Acepron and see your doctor immediately.
5. Acepron 500 mg . drug interactions
Drug interactions can change the action of the drug, reduce or completely lose its therapeutic effect. Acepron 500 mg may interact with the following drugs:
Acepron when used in high doses and for a long time can produce intermediate metabolites that are toxic to the liver, especially when used concurrently with Isoniazid drugs. , Alcohol, or anticonvulsants including Carbamazepine, Phenytoin, Barbiturates. Co-administration of Acepron 500 mg with Phenothiazines can potentially cause severe fever reduction in users. Metoclopramide will increase the absorption of Acepron when used at the same time. To avoid drug interactions, talk to your doctor about any medications you're currently taking. Your doctor will usually ask you to stop either medication, adjust the dose, or prescribe a more suitable medication.
6. Dealing with missed dose or overdose when taking Acepron 500 mg
When you forget a dose, you can use Acepron 500 mg as soon as you remember. However, if it is close to the time for your next dose, skip a dose and take the next dose at the prescribed time.
When the drug overdose, the patient may experience some symptoms such as nausea, vomiting, loss of appetite, paleness, abdominal pain.
For adults taking a high dose of more than 10g or a child taking a high dose of over 150 mg/kg can cause liver cell destruction leading to complete and irreversible necrosis. Patients may also experience some encephalopathy leading to coma or death. At this time, it is necessary to be immediately transferred to the hospital, gastric lavage to completely eliminate the amount of drug taken.
Above is some basic information about Acepron 500 mg. You can refer to the right dose, the right way.
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