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Dopagan 650mg contains the main active ingredient, Paracetamol, which has an effective antipyretic and analgesic effect. This is a very popular drug and is available at most drugstores today. The article will provide some general information about the use, dosage, side effects as well as notes during the use of the drug.
1. Uses of Dopagan 650
Dopagan 650 contains the active ingredient Paracetamol with a concentration of 650mg. It is widely used to treat mild to moderate pain and to reduce fever. Paracetamol's mechanism of action is to act on the thermoregulatory center in the hypothalamus causing vasodilation, increasing peripheral blood flow, thereby helping to reduce body temperature and reduce fever. Paracetamol has little effect on the cardiovascular and respiratory systems at therapeutic doses. The drug effectively relieves pain with pain of non-visceral origin. The drug does not affect platelet aggregation and gastric irritation.
Paracetamol is rapidly and almost completely absorbed after oral administration. The half-life of the drug is 1.25 - 3 hours. The drug is metabolized mainly in the liver, excreted by the kidneys in unchanged form and also as metabolites.
2. Dosage of Dopagan 650
The drug is used orally in the following doses:
Dosage for adults and children 12 years and older: Usually 325-650mg / time, 4-6 hours apart if necessary, but not more 4g/day. Larger doses (eg 1g/time) may be necessary in some cases. Note: If the patient has a high fever, lasts for more than 3 days or recurs frequently, they should go to a medical facility for quick examination, diagnosis and treatment.
3. What to do when overdose Dopagan 650?
Paracetamol overdose can be caused by a single high dose, repeated large doses (7.5 - 10g per day, for 1-2 days) or by long-term use. Hepatic necrosis is the most serious toxicity of paracetamol overdose and can be fatal. Signs of Paracetamol overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, confusion, weakness,... In severe poisoning, the patient may experience nervous system irritation. central to agitation, delirium. There may then be central nervous system depression leading to hypothermia, fatigue, tachycardia, weakness, irregularity, hypotension, and circulatory failure. Signs of liver damage become apparent within 2 to 4 days after poisoning. Liver enzymes are elevated and plasma bilirubin levels may also be elevated. The patient will have additional clinical symptoms such as upper abdominal pain, dark urine, jaundice or whites of the eyes. If not treated promptly, the patient will suffer severe liver damage and death.
4. What are the side effects of Dopagan 650mg?
Dopagan 650 may cause some of the following side effects:
Hepatotoxicity: Acute hepatotoxicity due to intentional or unintentional overdose in patients. In children, unintentional overdose can be caused by accidental ingestion, taking the drug more often than recommended, and using multiple products containing Paracetamol. Some factors increase the hepatotoxicity of Paracetamol including the elderly, alcoholism, using many products containing Paracetamol; Dermatology: Skin rash, bullae; Gastrointestinal: Anorexia, abdominal pain, nausea, vomiting; Blood: Hematopoietic disorders (neutropenia and pancytopenia), anemia.
5. Note when using Dopagan 650mg
Dopagan 650mg is contraindicated in cases of anemia with repeated recurrence or serious disease in the heart, lungs, liver, kidneys; Hypersensitivity to Paracetamol and other components of the drug. Use with caution in patients with G6PD deficiency; The drug can cause serious skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized pustular syndrome. Therefore, patients should pay attention to abnormal signs on the skin such as redness, rash, peeling. When having the above signs, the patient needs to stop taking the drug and go to a medical facility for examination; Patients who drink a lot of alcohol while taking the drug may increase the hepatotoxicity of Paracetamol. Therefore, alcohol should be avoided or limited while taking the drug; Pregnancy: Paracetamol crosses the placenta. However, current data suggest that drug use does not increase the risk of major birth defects. Overall, Paracetamol is considered suitable and safe to treat pain and fever during pregnancy. It is recommended to use the drug with the lowest effective dose and for a short time to protect the health of the fetus; Lactation: Paracetamol is excreted in breast milk. The drug is considered safe during breast-feeding if used at the recommended dosage; Dopagan 650 mg does not affect the ability to drive or use machines; There are a number of other drugs that can interact with Paracetamol if used concurrently. Therefore, you need to tell your doctor or pharmacist about all prescription and over-the-counter medicines, supplements, vitamins and minerals you are taking for advice. In summary, Dopagan 650mg is used for pain relief and fever reduction. Although widely used, the drug can cause serious side effects such as liver necrosis and death. Therefore, patients need to make sure to take the correct dose and seek medical attention if the pain or fever persists.
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