This is an automatically translated article.
The article was professionally consulted by Pharmacist Nguyen Thi Linh - Faculty of Pharmacy - Vinmec Danang International General Hospital.Acetazolamide is one of the drugs used to reduce intraocular pressure and treat glaucoma.
1. What is Glaucoma of the Eye?
Glaucoma is a term used to refer to a group of diseases of the optic nerve head, chronic progressive, characterized by visual field damage, atrophy of the optic disc and associated with elevated intraocular pressure.Glaucoma has many ways of classifying, currently in Vietnam it is often classified into:
Primary glaucoma (most concerned), including:
Primary closed angle glaucoma (common in Vietnam). Primary open-angle glaucoma. Secondary glaucoma: appearing after disorders in the eyes and the whole body, such as glaucoma due to trauma, uveitis, pathology of the vitreous,...
Glocom is dangerous in that if not detected and timely treatment, there will be no drug treatment or surgical intervention to restore the damage that glaucoma has caused. Affected people can go blind.
Bệnh Glocom ở mắt là bệnh lý nhãn khoa làm tăng nhãn áp quá giới hạn bình thường
2. What is Acetazolamide 250mg?
Acetazolamide is a carbonic anhydrase inhibitor. Inhibition of this enzyme reduces the formation of hydrogen and bicarbonate ions from carbon dioxide and water, reducing the availability of these ions for active transport, thus, acetazolamide reduces aqueous production and has a beneficial effect. lower eye pressure, application in the treatment of closed angle glaucoma, open angle glaucoma...
Acetazolamide was once used as a diuretic, but its effectiveness gradually decreased with continued use, so it was largely replaced by other drugs. such as thiazides or furosemide.
3. Acetazolamide dosage in the treatment of eye diseases
For open-angle glaucoma, adults need to take 1-4 times a day, 1 tablet each time at the starting dose and a smaller amount when taking the maintenance dose. Children take 3 times a day, the dose is specifically calculated based on the weight of each child. For secondary glaucoma or drug use for prophylactic purposes before ophthalmic surgery, take 1 tablet every 4 hours.
Acetazolamid là thuốc có công dụng làm giảm nhãn áp
4. Contraindications Acetazolamide
Acetazolamide is not used on the following subjects:
People who are sensitive to the ingredients in the drug. Pregnant women People with lactose intolerance People with liver failure, severe kidney failure, especially cirrhosis. People with hypokalemia, blood sodium as well as electrolyte balance disorders.
5. Acetazolamide side effects
Some side effects of Acetazolamide that users need to know before taking the drug, including:
Fatigue, headache, dizziness. Loss of appetite, change in taste Metabolic acidosis Fever, rash, rash. Nausea, vomiting Kidney stones Hypokalemia Sudden mood changes, possibly depression Decreased interest in sex When experiencing these side effects, the patient should see a treating doctor to report presenting the above symptoms to adjust the dose of the drug or to discontinue the drug in case of necessity.
Sử dụng Acetazolamid có thể gây đau đầu mệt mỏi
6. Notes when using Acetazolamide
Although it is effective in treating Glaucoma in the eye as well as other diseases, when using Acetazolamide, caution should be taken, especially for subjects such as:
Elderly people People with respiratory diseases Inhalation People with metabolic acidosis People with diabetes mellitus People who often drive and operate machinery: because the drug has side effects such as dizziness, visual disturbances, myopia...so it will affect to the health of these subjects while they were at work. Use caution when using for pregnant and lactating women, consult a doctor about drug use. Acetazolamide has the potential to interact with drug groups such as diuretics, corticosteroids, corticosteroids, amphotericin B, tricyclic antidepressants, barbiturates, carbamazepine, phenytoin, methenamine, cardiac glycosides, so it should be used with caution. avoid causing conditions such as hypokalemia, increased toxicity in the body.
Acetazolamide has therapeutic uses in many different diseases, especially in glaucoma in the eye. The drug should be used as prescribed by the doctor, avoid self-administered because it will cause serious unwanted effects to the patient's health.
Khám chuyên khoa Mắt tại Bệnh viện Vinmec
To meet the needs of patients for screening for eye diseases, Vinmec International Hospital now provides Glaucoma Packages to help customers detect diseases early and have effective treatment, prevent dangerous complications.
Currently, Vinmec is implementing 2 packages of Glaucoma examination and treatment, including: Glaucoma early detection package and scleral trabeculectomy package to help:
Comprehensive eye examination and indication for surgery (if any) by experienced medical specialist. Advice on drugs, food, factors that can affect surgery.. Anesthesia examination and resuscitation assess the patient's general condition before surgery. Explain surgical prognosis.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
