This is an automatically translated article.
The article is professionally consulted by Master, Doctor Nguyen Huy Nhat - Department of Medical Examination & Internal Medicine - Vinmec Danang International General Hospital. Doctor Nguyen Huy Nhat has many years of experience in the field of respiratory disease treatment.NO is a common intra- and intercellular messenger and has many physiological roles in the body, such as assessing airway inflammation in asthma, predicting response to corticosteroids or supportive care. respiratory support in pediatric patients with aspiration pneumonia, premature birth.
1. The role of NO gas in asthma
Evaluation of airway inflammation in asthmatic patients: NO is a common intra- and intercellular messenger and has many physiological roles. NO synthesis is increased in response to the body's inflammatory response, so NO can be used as a surrogate marker for acute or chronic inflammation. Measuring NO in exhaled air can help diagnose asthma when clinical symptoms are atypical and pulmonary function tests are normal. Assessment of Asthma Control: Changes in exhaled NO concentrations are also correlated with the degree of asthma control. When this index is reduced by 40% or more from baseline, it is equivalent to well-controlled asthma. Helps predict response to corticosteroids: Many articles have shown that exhaled NO concentrations are similar associated with eosinophilic inflammation, which is a corticosteroid-sensitive form of inflammation. As a result, NO becomes an effective tool to predict response to corticosteroids better than other lung tests. A recent study extended the predictive value of exhaled NO in the assessment of response to corticosteroids in other asthma phenotypes, including non-eosinophilic asthma. Corticosteroid dose adjustment: There is currently ample evidence to support the use of exhaled NO for dose adjustment of inhaled corticosteroids in adults. In children, the evidence is not yet complete.
Khí No khá quan trọng trong bệnh hen
2. Role in respiratory support for pediatric patients
NO gas has the ability to dilate pulmonary blood vessels, thereby reducing pulmonary resistance for blood to flow to the lungs, helping the lungs to exchange gases to improve the respiratory failure of pediatric patients. NO gas is indicated in the following cases: Premature pregnancy with aspiration pneumonia caused by aspiration of amniotic fluid in the womb, children with blood infections, children with complications of pulmonary hypertension, premature babies born when the mother is not yet due. labor and respiratory failure due to immature lungs, congenital diaphragmatic hernia, and some children with pulmonary hypertension of unknown cause.Vinmec International General Hospital is one of the hospitals that not only ensures professional quality with a team of leading medical doctors, modern equipment and technology, but also stands out for its examination and consultation services. comprehensive and professional medical consultation and treatment; civilized, polite, safe and sterile medical examination and treatment space.
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