This is an automatically translated article.
Tacropic is a topical cream used to treat cases of atopic eczema that have not responded to conventional medical measures. However, even if used topically, the drug can sometimes cause some side effects.
1. What are the effects of Tacropic?
The main ingredient of Tacropic is Tacrolimus 10 mg/10 g (0.1%) formulated as a topical cream.
Tacrolimus is a potent immunosuppressive agent similar to cyclosporin in terms of pharmacological activity but not structurally related; This drug also has antibacterial activity but is very limited. The exact mechanism underlying the immunosuppressive effects of tacrolimus is currently unknown. When this ointment is applied to the skin of patients with atopic dermatitis, it improves skin lesions. This improvement is associated with a decrease in the Fc receptor in Langerhans cells, which reduces the over-stimulating effect on T lymphocytes.
Therefore, Tacropic is used to treat atopic eczema in patients who do not respond to or are intolerant to conventional medications.
2. Tacropic side effects
When taking Tacropic you may experience some unwanted effects. The side effects of Tacropic include:
Common side effects:
Local skin reactions: Burning, erythema, soreness, irritation, paresthesia, rash, itching and inflammatory skin reactions at the site. dosing site. Infections: Herpes virus infection causes herpes simplex dermatitis, folliculitis, herpes simplex lip, and Kaposi's varicella-like rash. Allergies cause itching on the skin. Nervous system: Paresthesia and sensory disturbances such as hyperesthesia, burning sensation. Causes alcohol intolerance with facial redness or skin irritation after consuming alcoholic beverages. Rare side effects:
Causes acne , edema at the site of application Although a relationship between the use of the drug and rare cases of malignancies including malignancy of the skin and lymph nodes, but this condition has been reported in patients receiving tacrolimus ointment. While using tacrolimus, you should limit your skin's exposure to sunlight or artificial light. When experiencing side effects of the drug, you need to stop using it and notify your doctor or immediately go to the nearest medical facility for timely treatment.
3. Things to keep in mind when taking Tacropic
The drug is contraindicated for cases with a history of hypersensitivity to any component of the drug. Do not give this medicine to children under 2 years of age. Patients with atopic eczema are more prone to skin infections. If a clinical skin infection is present, the risks and benefits of using Tacropic should be weighed, as its use may increase the risk of a more serious skin infection. Patients with Netherton syndrome have been reported to have an increase in blood levels of tacrolimus following topical administration of tacrolimus ointment. The possibility of increased drug absorption should be considered after topical administration of tacrolimus ointment in patients with Netherton's syndrome. The safety and efficacy of tacrolimus as a topical drug have not been evaluated in children under 2 years of age. Therefore, do not use for children under 2 years old. The drug has also not been evaluated for safety and effectiveness in patients with generalized erythroderma. The use of Tacropic has not been specifically studied in pregnant women. Tacropic should be used during pregnancy only if the benefit to the mother outweighs the risk to the fetus. Lactation: Tacropic is excreted in human milk following systemic administration. Therefore, caution should be exercised when using Tacropic ointment during lactation. When using, you need to clean the area of the skin to be applied before applying the medicine and should only use a thin layer of the medicine on the skin to be effective and reduce the risk of side effects.
If you see signs and symptoms of atopic eczema while taking the drug, you should see a doctor again because continued use or not should be considered.
Concomitant use of Tacropic with UVA, UVB or in combination with psoralen (PUVA) therapy should be avoided. Because it can increase the risk of damage to the skin. Use sunscreen and sunscreen if you must be out in the sun while taking this medicine.
Storage: After taking the medicine, close the lid tightly to avoid contamination of the medicine. Store the medicine in a dry place, protected from light, at a temperature below 30 degrees Celsius, out of the reach of children. Do not use the medicine after the expiry date and signs of deterioration.
Hopefully through the article you know what Tacropic medicine treats and the possible side effects when using it. To limit side effects, you need to be careful about the dose and use it according to the instructions of your doctor.
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