Sorbitol: Uses, indications and precautions when using

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Sorbitol is used as a laxative to treat occasional episodes of constipation. Depending on the brand, this product may be taken orally and/or rectally. Some products can only be offered directly. The following article will provide information about the uses, indications and notes when using Sorbitol.

1. What is Sorbitol?, uses of Sorbitol?

Sorbitol, also known as D-sorbitol, 50-70-4, E420 and D-glucitol, is a type of carbohydrate. It belongs to the class of sugar alcohols also known as polyols.
This water-soluble compound is found naturally in a number of fruits, including: apples, apricots, dates, berries, peaches, plums, and figs.
It is also commercially produced from corn syrup for use in packaged foods, beverages and medicines.
Sorbitol is commonly used to maintain product moisture as well as to add sweetness and texture to products, thus being used commercially. In addition, sorbitol also has the ability to assist in promoting gastrointestinal and oral health.
Sorbitol is used to relieve occasional and unusual constipation. Sorbitol typically produces a bowel movement in 1/4 to 1 hour when administered rectally.
Sorbitol is also used as a pharmaceutical auxiliary (sweetener).

2. How to use Sorbitol

If you are taking this medication by mouth, follow your doctor's directions.
If you are using this medication rectally, prepare the enema properly as directed on the product package or as directed by your doctor.
Do not use for longer than a week and do not take with laxatives or stool softeners unless directed by your doctor.
Laxatives should only be used temporarily until normal bowel habits return. Prolonged use may lead to laxative dependence.
Dosage of Sorbitol:
Strength and Dosage Forms for Adults and Children
Irrigation Solution
3 g / 100mL (3%) Oral Solution
70% Dosage:
Constipation
Adults, Oral: 30-150 mL (70% solution) once Adults, rectal enema : 120 mL 25-30% solution once Children under 2 years: Safety and effectiveness have not been established Children 2-11 years: Oral: 2 mL/kg (as 70% solution) once Rectal: 30-60 mL as 25-30% solution Children 12 years and older: Oral: 30- 150 mL (70% solution) once Rectal enema: 120 mL 25-30% solution once sodium Polystyrene Sulfonate support
Adults: 15ml 70% solution or 10-20ml/2 hours orally until digested Diarrhea occurs Children under 12 years of age: Safety and efficacy have not been established Children 12 years of age and older: orally 15 mL of 70% solution or 10-20 mL every 2 hours until diarrhea Procedure transoral surgery
3-3.3% when irrigated during surgical procedures

3. Side effects associated with the use of sorbitol

Common side effects of sorbitol include:
Abdominal discomfort Dehydration Diarrhea Dry mouth Intestinal overactivity Loss of fluids and electrolytes High blood sugar (hyperglycemia) Lactic acidosis Nausea Swelling (edema) Vomiting Some allergic reactions may occur such as: dizziness, difficulty breathing, itching/swelling (especially of the face, tongue, throat), rash.
All of the above side effects do not include all side effects of the drug. Get medical help right away if any of these serious side effects occur: Rectal bleeding, vomiting, weakness, dizziness, constant urge to have a bowel movement. Call your doctor or get medical help right away if the following very unlikely but very serious side effects occur: black, tarry stools.

4. Drugs that interact with Sorbitol

If your doctor prescribes this medication for you, make sure they are aware of possible drug interactions and monitor and advise you. Do not use, stop or change the dose of any medicine without consulting your doctor, pharmacist or medical facility.
Serious sorbitol interactions include:
Sodium polystyrene sulfonate Moderate interactions of sorbitol include:
Deflazacort Dichlorphenamide Sorbitol has no known mild interactions with other medications.
The above interactions do not include all possible interactions or side effects. So tell your doctor or pharmacist about all the medicines you are taking. Remember all your medication lists and tell your doctor or pharmacist about them. Please consult your doctor or pharmacist if you have questions or concerns about your health condition or would like more information about medication information.

5. Warnings and Precautions for Sorbitol

Warning This medicine contains sorbitol. Do not take sorbitol if you are allergic to sorbitol or any of the ingredients in this medicine.
Keep out of reach of CHILDREN.
Contraindication Anuria , acute abdominal pain, nausea, vomiting, or other symptoms of abdominal appendicitis or undiagnosed pain Effects of drug abuse
No information available Overdose
If you have overdosed and have severe symptoms such as fainting or difficulty breathing, call your doctor immediately and go to the nearest medical facility. If you use too much, it can cause stomach cramps, diarrhea.
Caution
Patients with heart failure and acute pulmonary edema or chronic kidney failure Dehydration, electrolyte abnormalities. The patient is unable to metabolize sorbitol. Pregnancy and breast-feeding
Use sorbitol with caution during pregnancy if the benefits outweigh the risks. No human studies have been performed, some animal studies suggest a risk. Use caution when using sorbitol if you are breastfeeding. Consult your doctor. Note
Do not share this medicine with others
Consult your doctor for a constipation prevention plan that is right for you. The plan may include drinking more fluids, increasing the amount or fiber in your diet, and exercising regularly.
Missed second dose
If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose, use the next dose at the usual time
Storage
Store at room temperature, away from light and moisture. Refer to the storage information printed on the bottle for exact temperature ranges. If you have any questions about storage, ask your pharmacist. Do not store in the bathroom. Keep out of reach of children and pets.
Do not arbitrarily flush the medicine down the toilet and pour it into the drain. Or dispose of medication appropriately if it is expired or no longer in use.. Consult your pharmacist or local waste disposal company for details on how to dispose of your product. safely.

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Reference sources: webmd.com, healthline.com, rxlist.com