Principles of treatment of peptic ulcer disease in children

This is an automatically translated article.

The article was written by Specialist Doctor II Bui Thu Huong - Head of Emergency, Day Treatment Unit, Pediatric Center - Vinmec Times City International Hospital.
Peptic ulcer disease is a disease that causes inflammation and ulcers on the lining of the stomach or duodenum (the first part of the small intestine). These injuries occur when the lining (the innermost lining) of the stomach or duodenum is worn away and the layers below the stomach or intestinal wall are exposed. The principle of treatment is based on the concept of the pathogenesis of the disease.

1. Treatment goals

1.1 Antacids 1.2 Anti-acid drugs Drugs that inhibit H2 receptors at the receptor on parietal cells make histamine H2 ineffective. Brand name: Cimetidine, Ranitidine, Famotidine,...

1.3 Mucosal protection (enhanced protective factors): Sucralfate, Bismuth 1.4 Proton pump inhibitors Mechanism: inactivation of the enzyme H+/K+ ATPase (Proton pump) Brand name: Omeprazole, Lansoprazole Pantoprazole, Esomeprazole, Rabeprazole

2. Indications for treatment of H.pylori infection in children

Confirmation of H. pylori positive by reliable tests in children:
Gastrointestinal symptoms and lesions on endoscopic/histopathology Iron deficiency anemia with no known cause Hematuria Autoimmune coccidiosis with no known cause The first choice to treat H.pylori infection is a 3-drug combination regimen including 2 antibiotics and PPIs, used twice a day Treatment duration 14 days Bacterial culture and antibiogram should be done, especially in communities with high rates of antibiotic resistance, and cases of treatment failure.

When babies have been diagnosed with gastritis, they should go to a specialist doctor to be treated according to the right regimen.
Pediatrics department at Vinmec International General Hospital is the address for receiving and examining diseases that infants and young children are susceptible to: viral fever, bacterial fever, otitis media, pneumonia in children, .... With modern equipment, sterile space, minimizing the impact as well as the risk of disease spread. Along with that is the dedication from the doctors with professional experience with pediatric patients, making the examination no longer a concern of the parents.

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