Phytok - Vitamin K1 drops: Information to note when using

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1. Ingredients, dosage form of Phytok Phytok is prepared in the form of an oral emulsion, each 1 ml of drug solution contains 20 mg of vitamin K1 (phytomenadion), 1 drop is equivalent to 1 mg of vitamin K1.
Vitamin K1 is one of the important components involved in the synthesis of clotting factors.

2. Indications of Phytok Phytok are used in case of vitamin K deficiency that cannot be supplemented through nutrition, specifically in the following cases:
Prophylaxis for children immediately after birth Prevention of deficiency vitamin K given to infants born to mothers receiving antiepileptic, anti-tuberculosis, or coumarin derivatives. Prophylaxis in patients with risk factors for vitamin K deficiency with a low Quick value or an INR above the upper limit of the norm as in the following: Patients with intestinal malabsorption syndrome Ingestion or long-term parenteral nutrition, patients with cholestasis (biliary obstruction, alpha-1 antitrypsin deficiency, cystic fibrosis, Cytomegalovirus infection). Patients with pancreatic disease, betalipoproteinemia, cytomegalovirus infection, treatment with antibiotics (such as cephalosporins), sulphamides and salicylates. Treatment of patients with vitamin K deficiency bleeding, most with Quick value less than 10% or INR ≥ 5. Bleeding from vitamin K deficiency can occur with inadequate absorption of vitamin K. K or after an overdose of coumarin derivatives.

3. Notes when using Phytok Phytok drugs are taken by mouth directly. In all cases, use the drug only if prescribed by your doctor. The usual dosage is as follows:
3.1. Prophylaxis Healthy newborns from 36 weeks gestation and up: take the first dose of 2mg vitamin K1 (equivalent to 2 drops of Phytok) right after birth. After 3 - 10 days of taking the second dose, the dose level is 2 mg of vitamin K1. The third dose is taken 4-6 weeks after birth, using 2mg vitamin K1. For formula-fed babies, the 3rd dose can be skipped. Pregnant women taking anti-epileptic and anti-tuberculosis drugs: use 10-20mg of vitamin K1 (equivalent to 10-20 drops of Phytok) in the morning. about 8 to 48 hours before birth. Patients with risk factors for vitamin K deficiency with a low Quick value or an INR above the standard limit: 2.5-25 mg of vitamin K1 or more if needed (but usually not to exceed 50mg) Dosage and route of administration depend on the clinical condition and response of the patient. Oral administration only when clinical disturbances do not preclude gastrointestinal absorption. Should be taken with bile salts if the source of endogenous bile salts is not enough. Stop or reduce the dose of drugs that affect the clotting mechanism if possible
3.2. Treatment of bleeding due to vitamin K1 deficiency Patients with light bleeding due to vitamin K deficiency: use 1 - 5mg of vitamin K1 (equivalent to 1 - 5 drops of Phytok) (applicable to both infants and adults) Patients with bleeding Mild bleeding due to an overdose of anticoagulants should temporarily stop using the drug and use vitamin K1 at a dose of 1 - 5mg (equivalent to 1 - 5 drops of Phytok) Patients with severe bleeding: take vitamin K1 at a dose of 5 - 10mg (equivalent to 5 - 10 drops of Phytok) will increase the prothrombin complex. The following drugs may interact with vitamin K1 and may reduce the effectiveness of vitamin K1: anticoagulants coumarrin, salicylates 4-6g daily, some antibiotics.
The ampoules must be put into the box immediately after use and the lid of the box tightly closed to avoid loss of drug quality due to exposure to light.
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