Nelarabine: Uses, indications and precautions when using

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The drug NELARAbine has the generic name NELARABINE. Nelarabine is administered intravenously. Nelarabine is used to treat certain types of cancer.

1. Uses of the drug Nelarabine

Nelarabine is effective in the treatment of certain cancers such as leukemias and lymphomas. Nelarabine is a chemotherapy drug that works by slowing or stopping the growth of cancer cells.

2. How to use the drug Nelarabine

Before using the medicine, read the instructions on the drug information leaflet and follow the instructions from your doctor. Nelarabine is given by slow intravenous injection. Each phase of treatment is called a cycle. In adults, the drug is usually given on days 1, 3, and 5 of each treatment cycle or as prescribed by your doctor. In children, it is usually taken daily for 5 consecutive days in each treatment cycle or as prescribed by your doctor.
The amount of medicine that enters your body will be based on your medical condition, age, and how well your body responds to treatment. Before proceeding to the next stage of treatment, your doctor will check your blood count analysis first to make sure that your readings are stable for the next treatment.

3. Possible side effects when using Nelarabine and precautions

The use of Nelarabine can lead to serious side effects including headache, nausea, vomiting, loss of appetite, constipation, diarrhea, cough, shortness of breath, dizziness, always Drowsiness and general fatigue appear. In certain cases, the doctor may prescribe medication to prevent or reduce the feeling of nausea and vomiting to avoid causing discomfort to the patient. To help reduce the effects of these effects, doctors often advise patients to eat small meals, not eat before treatment, or limit vigorous physical activity. If the above conditions do not improve but persist, please inform your doctor to find a solution.
When using the drug, there may be serious side effects, tell your doctor right away if you have the following problems, including a light bump, easy bruising or bleeding, swelling of the ankle area , foot. This medicine may decrease the body's resistance. Tell your doctor right away if you have any signs of an infection such as fever, chills, or a persistent sore throat.
Nelarabine sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, your doctor may add a medication and ask you to drink lots of water. Tell your doctor right away if you have symptoms such as low back pain, pain in your side (costal pain), signs of kidney problems such as painful urination, bloody pink urine, Change in urine output, muscle spasms, muscle weakness.
Cases of drug use followed by a very serious allergic reaction are very rare. However, you should get medical help right away if you notice any of the following symptoms including a generalized rash, itching, swelling (especially in the face, tongue, and throat area), dizziness and difficulty breathing. This is not a complete list of possible side effects when taking Nelarabine. If you notice other effects on your body after taking this medicine, which are not listed above, talk to your doctor or pharmacist for more information.
Before using nelarabine, tell your doctor or pharmacist if you are allergic to the drug or its ingredients, or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of blood disorders such as anemia, seizures or convulsions. Do not self-administer vaccines without your doctor's consent, and avoid contact with people who have recently received oral polio vaccine or inhaled influenza vaccine. Pay attention to clean hands and feet to avoid spreading infection. Avoid contact with people who have the flu or chickenpox. To reduce the risk of injury, bruising or bleeding, be careful with sharp objects such as razors, needles, etc.
Before having another surgery tell your doctor about what you are using use this drug. Nelarabine can make you drowsy and dizzy, so do not drive, use machines, or do anything that requires alertness or concentration until you are sure you can do them safely. safe.
Older adults may be more sensitive to the side effects of this medicine, especially nervous system problems such as numbness and tingling in the limbs. For women planning to become pregnant, pregnant women and nursing mothers need to be extra careful, so consult your doctor to use Nelarabine safely and effectively.

4. Nelarabine drug interactions

The use of different drugs in the course of treatment may cause the good effects of the drug to be altered or reduced. Therefore, it is very important to know about the medications you have been taking before starting treatment. So that the doctor can adjust the dose so that it is most suitable, the unwanted nature of the risk.
Some products that may interact with this Nelarabine include other anticancer drugs (especially pentostatin). Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain relievers or cough medicine (such as codeine, hydrocodone), alcohol, stimulants, narcotics, sedatives such as: alprazolam, lorazepam, zolpidem, or antihistamines (such as cetirizine, diphenhydramine).

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Reference source: webmd.com