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Acne is one of the most common skin diseases that occur during puberty due to hormonal changes in the body and lasts into adulthood. Acne can occur in 80-90% of young people to varying degrees and about 20-30% of these need to be supported by medical therapy. Currently, Adapalene or Differin is an effective acne medication with distinct characteristics.
1. What is Adapalene? Mechanism and dosage used?
Adapalene, also known as Differin, is a drug with a tretinoin-like mechanism of action that binds to retinoic acid receptors but does not bind to receptor proteins in the cytoplasm. differentiation of the epidermis. Adapalene is anti-inflammatory by inhibiting the chemotactic and hyperactive responses of human polymorphonuclear leukocytes and also by clipoxidation of arachidonic acid to proinflammatory mediators.Adapalene is indicated topically for the treatment of acne in the presence of comedones, papules and pustules. The drug can be used for acne on the face, chest and back. Apply on both acne-affected skin once a day before resting and cleansed skin. Should apply a thin layer to avoid contact with eyes and lips, dry skin before application. Some notes when using the drug include:
If the drug is overdosed, it can cause irritation causing the skin to become red, peeled or difficult. bear, rash. Contraindications of the drug are patients who are allergic to any component of the drug. Do not let the medicine come into direct contact with the eyes, mouth or nasal cavity, mucous membranes, if any, rinse immediately with warm water. Do not apply on broken skin or eczema, patients with severe acne. The drug should not be used by pregnant and lactating women because the drug is excreted in breast milk.
2. How to use Differin gel?
The steps to use Differin gel are as follows:
Wash your hands thoroughly before applying the medicine and at the same time clean the acne-affected skin with a mild soap-free cleanser and then pat dry. Use your fingertips to apply a thin layer of medication to the skin. Apply once daily at bedtime or as directed by your healthcare professional. The drug is for use on the skin only. During the first few weeks of using Adapalene (Differin), acne may get worse because it works deep inside, so it can take 8-12 weeks to see the effect of the medicine.
Use the medicine regularly for maximum benefit, should apply at the same time every day to create a habit that is easy to remember, applying more than the recommended dose can cause complications such as red, peeling skin, hurt.
Medicines are available in pharmacies, so choose reputable places and the type of medicine depends on the doctor's prescription. Notify your doctor immediately when the skin condition worsens so that appropriate adjustments can be made.
Patients with acne can go to Vinmec International General Hospital for examination and treatment. There is a team of well-trained, experienced and professional dermatologists; system of modern equipment, meeting international standards; Professional service quality, high efficiency in diagnosis and treatment.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.