This is an automatically translated article.
The article is professionally consulted by Master, Resident Doctor Nguyen Thi Tam - Clinician - Reproductive Support Center - Vinmec Times City International Hospital.Currently, day 5 embryo culture and transfer is a trend of many assisted reproductive centers around the world. Blastocyst stage embryo transfer offers a higher success rate than day 3 embryos because the implantation potential of day 5 embryos is higher than day 3 embryos.
1. What is day 5 embryo transfer?
In vitro fertilization, also known as IVF, plays an important role in the treatment of infertility and infertility. During in vitro fertilization, the egg and sperm are combined outside the body to form an embryo. The embryo is then inserted into the woman's uterus to develop into a fetus.Evaluation of embryo quality is an important step to make the correct selection of embryos to transfer, contributing to increased pregnancy rates.
What is embryo transfer on day 5 : After fertilization, the egg forms a zygote, it is raised outside the body for 5 days to form a blastocyst and then transferred to the uterus. At this stage, the blastomeres begin to transform and divide into two parts: the intrablastic mass, which develops into the baby's body, and the trophoblast, which develops into the appendages of the fetus later.
Thụ tinh IVF là phương pháp chữa vô sinh hiếm muộn hiệu quả nhất hiện nay
2. Is embryo transfer on day 5 high success rate?
Is there a high success rate for day 5 embryo transfer? Day 5 embryo culture technique is an advanced technique, providing a chance to get pregnant after embryo transfer for infertile couples because the implantation potential of day 5 embryo is higher than that of day 3 embryo. success is about 50%.Some other advantages when transferring embryos on day 5 such as:
Reducing the risk of multiple pregnancies because when transferring embryos on day 5 with high implantation potential, the number of embryos to be transferred will be reduced, depending on the mother's age and embryo quality to decides the number of embryos to transfer, in most cases, the mother only needs to transfer 1-2 embryos, thereby reducing the risk of multiple pregnancies and pregnancy complications caused by multiple pregnancies. Preimplantation genetic testing is safer because day 5 embryos have hundreds of cells for screening biopsies to select good embryos, eliminate embryos with chromosomal abnormalities, and increase mortality success after embryo transfer. Currently, most of the HTSS centers around the world implement the technique of embryo transfer to day 5. Safer to freeze and thaw embryos: The process of freezing and thawing embryos before transferring does not affect the quality. embryo, the survival rate after disintegration reached nearly 100%.
Chuyển phôi ngày 5 giúp hạn chế đa thai và dị tật bẩm sinh
3. Factors affecting 5-day embryo culture results
Maternal age: Egg quality as well as embryo quality is affected by maternal age. The higher the maternal age, the lower the percentage of day 5 embryos. Quality and quantity of embryos on day 3: If the patient has many embryos on day 3, the possibility of developing embryos on day 5 will be higher and vice versa, so depending on the case, consider whether to raise embryos to day 5 or not. are not. Lab quality and embryologist experience: Embryos are a very sensitive object, so embryos must be provided with a good and stable environment system. The technique and experience of an embryologist are very important in embryo culture.4. Time-lapse embryo culture cabinet
It is a multi-compartment culture cabinet with integrated microscope and automatic camera in each compartment. This type of cabinet is modern and has many advantages today. In addition to combining the advantages of a multi-compartment culture cabinet, the cabinet is equipped with a camera to monitor and take pictures of embryos continuously (Time-lapse), which helps embryologists easily record information of zygote and embryo, rapidly detects division abnormalities that may not be detected when embryos are cultured using conventional incubators. From there, making a decision to choose the correct embryo to transfer, increasing the success rate of embryo transfer. Vinmec IVF Reproductive Center is the address of infertility treatment - infertility is chosen by many couples. So far, the Center has performed fertility support for over 1000 infertile couples with a success rate of 45% - 50%. This rate is equivalent to developed countries such as UK, USA, Australia,...With high professional qualifications and extensive experience, Vinmec IVF Center's experts are capable of developing synchronously and comprehensively deploying the most advanced assisted reproductive techniques today, helping to realize the dream of parenthood of hundreds of families across Vietnam.
Master, Resident Doctor Nguyen Thi Tam Psychology graduated as a General Practitioner at Hanoi Medical University in 2015 and graduated with a Master and Resident Doctor of Obstetrics and Gynecology at Hanoi Medical University in 2015. Hanoi. With expertise in reproductive support, Dr. Ly used to work at the National Hospital of Obstetrics and Gynecology. And now, Dr. Ly is working at the Center for Reproductive Support, Vinmec Times City International General Hospital.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
