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Posted by Master, Doctor Nguyen Le Thao Tram - Doctor of Diagnostic Imaging - Department of Diagnostic Imaging - Vinmec Nha Trang International General Hospital
Paget's disease of the breast is a form of skin disease, common in older women, first manifesting as lesions on the breast skin and around the nipple area. The following article will provide detailed information about Paget breast images.
1. Paget's disease of the breast is what kind of disease?
Paget's disease of the breast or Paget's disease of the nipple, is a form of malignant breast lesion caused by tumor cell infiltration into the nipple epidermis. Although most cases of carcinoma in situ are nodular or localized or invasive, in some cases Paget's disease is localized to the nipple-areola skin tissue with no underlying neoplasm.
Paget's disease of the breast accounts for 1-5% of all breast malignancies. The average age is mostly over 50 years old (53 - 59 years old). The disease presentation is characterized by inflammation and eczematous changes in the nipple and areola such as hyperpigmentation. Paget disease of the breast is divided into four stages. In the early stage (stage 0) there are often signs of itching, scaling and abnormal discharge in the nipples; Correspondingly, the lesion was localized to the epidermis only with no underlying ductal carcinoma in situ. In later stages, ductal carcinoma in situ can be localized just below the nipple (stage 1) to spread (stage 2) and become invasive ductal carcinoma (stage 3).
In most patients with paget disease of the breast, characteristic malignancies or paget cells are present in the outermost layer of the skin surface of the nipple when viewed under the microscope and may extend to the neoplasm. of milk ducts. The exact cause of paget's disease of the breast is currently unknown.
MORE: Risk factors for Paget's disease of the breast
2. Image of Paget's disease of the breast on imaging techniques
2.1. Mammals
The sensitivity of mammography to Paget's disease is only about 50%, radiologists can think of Paget's disease with some features such as thickening of the skin, nipple retraction, and diffuse malignant microcalcifications. localized or diffused around the sub-nipple site and subareolar opacities.
2.2. Breast Magnetic Resonance
Magnetic resonance imaging of the breast is the modality of choice for the evaluation and diagnosis of Paget's disease of the breast if clinical or mammographic evidence is insufficient to confirm breast cancer. On magnetic resonance imaging, Paget's disease will manifest by abnormal absorption of the nipples, or clustered lesions, distributed as lines. This is a manifestation of ductal carcinoma in situ associated with Paget's disease. In addition, breast magnetic resonance is also the optimal means to help evaluate lesions during and after treatment.
Breast cancer is a common cancer in women, it is estimated that every year around the world, many women die from this disease. Accordingly, if breast cancer is detected early, the prognosis for treatment is very high, even if it is completely cured and not recurred. Therefore, breast cancer screening is essential, especially for those at high risk of breast cancer.
Currently, Vinmec International General Hospital has been implementing a breast cancer screening package for women of different ages. At Vinmec, there is a full range of necessary medical equipment, a system of modern medical machinery to perform methods of examination, diagnosis, testing, imaging, and treatment of breast cancer at many stages. . In particular, at Vinmec, there is a system of mammography machines, 3.0 Tesla magnetic resonance imaging machines with Silent technology. Magnetic resonance imaging technology is the technology applied in the most popular and safest imaging method today because of its accuracy, non-invasiveness and non-X-ray use.
Accordingly, the examination process and diagnosis of breast diseases at Vinmec are performed by a team of highly qualified medical professionals who have undergone training and are technically certified, able to handle them quickly and effectively. Therefore, when using Vinmec's breast cancer screening and early detection package, customers can detect cancer even when there are no symptoms.
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References:
https://radiopaedia.org/articles/paget-disease-breast?lang=us