How to use height growth hormone for safety and effectiveness?

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Injecting height growth hormone is a cross-cutting topic, discussed by Prof. TS. Dong Kyu Jin - Chairman of the Korea Association of Metabolic Genetic Diseases and Doctor Vu Chi Dung - Head of the Department of Endocrinology and Metabolic Genetics (National Children's Hospital) shared at a seminar at General Hospital in Hanoi. Vinmec Times City International Faculty (Hanoi): "Using growth hormone for children".

1. What is growth hormone?

Growth hormone is called growth hormone (GH hormone for short), also known as somatotropic hormone (SH) or somatotropin. This hormone is secreted by the anterior pituitary gland. Growth hormone GH affects almost all tissues in the human body. synthesize cellular proteins, increase the breakdown of adipose tissue to release energy, reduce glucose use, GH also indirectly affects cartilage and bone tissue. The production of growth hormone GH is regulated by the body according to circadian rhythms, suitable for each stage of the body's development.

2. Treatment of growth hormone deficiency

Medicines containing growth hormone are synthetic preparations by biotechnology, recombinant human genes (hGH: human Growth Hormone), hGH is used in certain diseases, in which it can help to increase growth. height, used for children of growing age whose height is modest due to GH deficiency (must be confirmed with low blood GH levels by testing).
When injecting growth hormone as indicated for children of modest height (due to lack of GH hormone), if they do not have thyroid disease and have a complete diet, the child's height will improve. For children of short height but not due to lack of growth hormone GH, the use of hGH may not be effective.

3. Inject height growth hormone to improve physique

Prof. Dr. Dong Kyu Jin is the director of the Center for Children and Adolescent Health - Sungkyunkwan Medical University - Samsung Hospital. At the same time, he is the President of the Association of Metabolic Genetic Diseases in Korea.
With more than 30 years of experience in researching the use of height growth hormone, Prof. Dong Kyu Jin has treated many successful cases. The patient achieved a good adult height (instead of much shorter height without the injection of height growth hormone). Growth hormone has the effect of helping children develop bones, increase muscle, reduce fat tissue, enhance the body's immune response... to help improve physique.
Patients are started on growth hormone therapy after reaching 2 years of age and finished when the bone age is 14 - 15 years old (for girls) or 15 - 16 years old (for boys) or it can be stopped early when the child's growth rate is less than 2cm/year. However, patients must be closely monitored for 3-6 months to monitor response to treatment and detect possible short-term side effects early. According to GS. Jin, growth hormone deficiency can be caused by many causes: pituitary hormone deficiency (most common cause), genetic mutation, brain damage, cancer treatment effects or many unknown cases reason.

According to GS. Jin said that growth hormone injection is not a problem exclusive to the specialized field of endocrinology, but also closely related to imaging techniques and genetic analysis during diagnosis and treatment. hormones. Therefore, growth studies require global cooperation. If you want to improve your physical stature, you need synchronous solutions in medicine, nutrition, and exercise to achieve the desired improvements. Therefore, GS. Jin cooperated with Vinmec in this field after he learned that Vinmec health system will invest heavily in regenerative medicine and gene technology.

4. Current status of treatment for growth hormone deficiency in Vietnam

Using height growth hormone is a relatively new issue for many hospitals in Vietnam as well as for parents with children with low height growth. From 2003 - 2005, the National Children's Hospital started to treat the first cases of growth hormone deficiency. However, due to the fact that the drug must be used for a long time and is not covered by health insurance, not many patients participate in the treatment. In recent years, the number of patients receiving intervention has increased significantly.
According to Dr. Vu Chi Dung - Head of the Department of Endocrinology, Genetics and Metabolism - National Children's Hospital, said that currently, in Vietnam, growth hormone treatment has been used for diseases such as: growth hormone deficiency alone, chronic kidney failure. , Turner syndrome, children who are younger for gestational age and do not catch up with growth at 4 years of age or later, growth retardation (due to mutations in the SHOX gene on the X chromosome)... apply to young children or minors.

Dr. Vu Chi Dung also added: Recently, parents whose children have been diagnosed with the disease and prescribed treatment are very determined to treat their children. About 1 in 2 children diagnosed with the disease are treated. Many children with growth retardation go to the hospital when they have passed the golden stage, so the treatment results are not really as expected, so when parents see their children have the following symptoms, they should take them to the hospital. Pediatric endocrinologist for early examination:
The child's growth rate is quite slow, less than 4cm/year. Increase the layer of fat under the skin of the abdomen, round cheeks. Boys with small penises Childlike status (children are shorter in stature and face than children of the same age)

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