How many HPV vaccines are there to prevent cervical cancer?

This is an automatically translated article.

The article was professionally consulted by Specialist Doctor II Quach Nguyen Thu Thuy - Pediatric Center - Vinmec Times City International General Hospital.
Cervical cancer is the second most common disease in women worldwide. More than 95% of cervical cancers are found to be caused by the HPV virus. HPV stands for Human Papilloma Virus. There is currently no specific treatment for this disease, so the only way to reduce the incidence of this disease is to get vaccinated.
All women between the ages of 9 and 26 are recommended to get vaccinated against cancer. cervical cancer (HPV) as soon as possible. have had sex or have had HPV.

1. Learn about the HPV vaccine?

HPV (Human Papilloma Virus) - the main cause of cervical cancer, is a human tumor virus, transmitted through contact, sexual intercourse, from mother to child and can exist in the body. for a long time before developing the disease. There are more than 100 types of HPV, in which, types 16,18 have the highest risk of causing cancer. There is currently no specific treatment for this disease, so there is only one way to reduce the incidence of this disease, which is vaccination
HPV vaccine is considered safe and can be highly effective in protects women from diseases related to HPV types 16 and 18, the two main types that cause cervical cancer. The characteristics of cancers, if left for a long time, are more difficult to treat, so doctors recommend that girls from the age of 9 get vaccinated to ensure protection before being infected with this virus. The safe age for the vaccine to be most effective is under 26 and unmarried or sexually active women.

2. Commonly used HPV vaccines

Currently, there are two types of HPV vaccines used in Vietnam: Gardasil (USA) and Cervarix (Belgium). These two vaccines have some basic differences in terms of the number of preventable strains of HPV, the target population, the vaccination schedule, and the preventive effect.

2.1 Cervarix vaccine

Origin: Cervarix vaccine (GlaxoSmithKline - Belgium)
Cervarix vaccine protects against 2 strains of human papillomavirus 16 and 18, approved for use in women between the ages of 10 and 25 to prevent cancer cervical mail.
Includes 3 injections: 1st dose: is the day of the first injection.
Nose 2: 1 month after the first dose
Nose 3: 6 months after the first dose.
Benefits : Prevents cervical cancer
The best time to get the HPV vaccine is before you start having sex. That's why the U.S. Centers for Disease Control and Prevention (U.S. CDC) recommends getting this vaccine at age 11 or 12, or as early as possible starting at age 9. If your child is 13 years or older and has not been vaccinated, you can still get the vaccine after the age of 26. In Vietnam, the HPV vaccine as recommended by the vaccine manufacturer is only given to women in ages 9 - 26 years
Cervarix vaccine: If it is necessary to change the vaccination schedule, the 2nd dose can be given 1 to 2.5 months after the 1st dose and the 3rd dose at the time of vaccination. score 5 to 12 months after the first dose.
Currently there is no recommendation for booster injection
How to use: Cervarix is ​​used for intramuscular injection into the deltoid region

2.2 Gardasil vaccine

Origin: Gardasil vaccine (Merck Sharp & Dohme - USA)
Gardasil vaccine: protects the body against 4 strains of human papillomavirus 6, 11, 16 and 18. Food and Drug Administration (FDA) The Food and Drug Administration (FDA) of the United States has approved it for use in women between the ages of 9 and 26 to help prevent genital warts and cancers of the cervix, vagina, clitoris, and anus. Gardasil is also approved for use in men 9 to 26 years of age to prevent genital warts and anal cancer.
Includes 3 injections: 1st dose: is the day of the first injection.
Nose 2: 2 months after the first dose.
3: 6 months after the first dose.
Effects: Prevention of cervical cancer, vulvar cancer, vaginal cancer, genital warts and anal cancer
Cancer of the cervix, vulva, vagina: due to the ingredients in 2 types 16 and 18. Genital warts (genital warts): because there are 2 types 6 and 11 in the composition. When the injection cannot be given according to the schedule, a flexible injection schedule can be applied as follows: 2-way injection 1st dose at least 1 month, and 3rd dose at least 3 months apart from 2nd dose.
How to use:
Gardasil vaccine is indicated for intramuscular injection of the deltoid muscle of the arm or into the anterolateral region of the upper thigh. The 0.5ml single dose vaccine is intended to be administered as-is, without the need to reconstitute or dilute the vaccine. The vial should be shaken well before injection. After shaking Gardasil will be a white turbid liquid. Before use, if a foreign object or abnormal physical sign is observed, it should be removed, and the vaccine must not be administered. Use a sterile syringe to remove 0.5 ml of vaccine from the vial. The vaccine should be given as soon as it is removed from the vial.

Vinmec International General Hospital always uses high-quality vaccines, with clear origin, suitable for the age to be vaccinated, ensuring safety from registration, storage to use.
Customers will be examined by specialist doctors, fully screened for physical and health problems, advised on preventive vaccines and injection regimens, how to monitor and take care of them after vaccination before when ordering vaccines according to the latest recommendations of the Ministry of Health & World Health Organization to ensure the best effectiveness and safety for customers. The team of doctors and nurses are experienced, professional, understand psychology and apply effective pain relief methods for customers during the vaccination process. 100% of vaccinated customers are monitored 30 minutes after injection and reassessed before leaving. Undertake medical supervision before, during and after vaccination at Vinmec Health System and always have an emergency team ready to coordinate with the vaccination department to handle cases of anaphylaxis, respiratory failure - circulatory arrest, ensuring Ensure timely and correct handling when incidents occur. Vaccination room is airy, feels comfortable like walking and has a good mentality before and after vaccination. Vaccines are imported and stored in a modern cold storage system, with a cold chain that meets GSP standards, keeping vaccines in the best conditions to ensure quality. Parents will receive a reminder message before the vaccination date and their child's vaccination information will be synchronized with the National Immunization Information System.

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