This is an automatically translated article.
Gamma GT index is a very important liver enzyme test index to assess the health status of people through the investigation of liver function, whether the liver is functioning normally or not. In addition, the Gamma GT index in the blood also contributes to finding the cause of liver dysfunction in order to have appropriate and effective treatment.
1. What is Gamma GT in blood?
Gamma GT index, scientifically known as Gamma Glutamyl Transferase, is one of the three most important liver enzymes in the body to help the liver function normally. GGT is abundant in organs such as kidney, pancreas, spleen, small intestine, liver... GGT is attached to the cell membrane and produces isopeptide of Glutamate with free amino acids, releasing the Dipeptide Cysteinyl- Glycine from Glutathione. GGT enzyme has the main function is to transport amino acids across cell membranes, can be transported very quickly at high intensity in the kidney or some other organs with special amino acids.
Pathologically, the determination of the Gamma GT index can help diagnose liver cholestasis, this index has a higher diagnostic value than those of other enzymes because of its sensitive nature. sensitive to cholestatic changes occurring in the liver. Besides, some other diseases with changes in GGT blood biochemical index are chronic hepatitis, pancreatic disease, myocardial infarction...
Chỉ số Gamma GT giúp phát hiện bệnh lý gan
2. How much Gamma GT is dangerous?
When the blood biochemical index GGT is higher than normal, it can be a sign of impaired cell membrane permeability in the liver as well as an increased rate of GGT enzyme synthesis in the liver. Causes of the increase in GGT index can be due to:
Liver disease, bile in the liver, especially cholestatic syndrome, chronic viral hepatitis, anemia to the liver, tumor in the liver, cirrhosis of the liver , liver failure... Due to drinking a lot of alcohol or foods containing alcohol, using certain drugs such as antidepressants, antiepileptic drugs, sleeping pills, antihypertensive drugs, antidiabetic drugs, antidiabetic drugs leprosy, oral contraceptives... Some other secondary causes but cause consequences on the liver such as myocardial infarction, heart failure, pancreatitis, congestion, diabetes, acute pancreatitis.. Normally, the Gamma GT index is at 60 UI/L, the liver is in a normal state of operation, which is a safe threshold for the human body, which can be more clearly distinguished as 11-50UI/L in men and 7. -32UI/L in females. The GGT index doubles the normal value if the liver damage is mild. In more serious cases, the liver is severely damaged, the GGT blood biochemical index may increase 2-5 times higher than normal, signaling that the patient needs to be diagnosed and treated as soon as possible. Some other acute diseases such as acute hepatitis or possibly liver cancer, the Gamma GT index sometimes reaches a very high threshold of 5000UI/L, requiring the patient to do additional tests necessary to conduct the procedure. treatment of liver damage.
When a patient has a high ALP test, the next order may be a Gamma GT test to evaluate the function and functioning of the liver as well as find the reason why the ALP index is increased, especially in patients with no clinical symptoms. If the GGT is within the normal range and the ALP is elevated, it is likely that the patient has a bone problem. In other cases, the Gamma GT test is done with some other tests such as AST, ALT to check liver function as well as detect liver diseases. Some manifestations of liver damage that patients need to pay attention to to immediately go to a medical facility performing Gamma GT test to check are weak body, fatigue, loss of appetite, nausea, vomiting, swollen abdomen , pain, jaundice, dark urine, pale stools, itchy rash all over the body...
Tình trạng vàng da kéo dài cần được xét nghiệm GGT
The test results show that the Gamma GT index is elevated, the patient needs to follow the doctor's next instructions, perform some necessary next tests including:
Hepatitis B and C tests, for hepatitis B test, it is necessary to do HBsAg, HBeAg, HBsAb, anti-HBeAg, viral DNA quantitative test... If there are signs of bile duct obstruction, measures should be taken. to treat the root cause of the disease. Stop drinking harmful drinks such as wine, beer, alcoholic water... Do not eat foods high in animal fat, fried foods... Have a reasonable exercise habit. Regularly check health periodically to monitor and promptly detect abnormalities.
Thường xuyên kiểm tra sức khỏe định kỳ là việc làm cần thiết
In order to protect health, it is extremely important for each person to have regular check-ups and check-ups, including the GGT blood biochemical index test. The GGT index test helps to assess the functional status and activity of liver cells, one of the most important organs in the human body.
To register for examination and treatment at Vinmec International General Hospital, you can contact Vinmec Health System nationwide, or register online HERE
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