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Abiraterone is commonly used in the treatment of prostate tumors along with certain other medications. So what is Abiraterone and how is it used?
1. Uses of the drug Abiraterone
Abiraterone has the main ingredient abiraterone acetate, which is prepared in the form of oral tablets with the strength of 125 mg; 250 mg; 500 mg.
Abiraterone works to reduce androgen production in the body. Androgen is a male hormone that can promote the growth of tumors in the prostate gland in men.
Abiraterone is used together with steroid medicines (such as prednisone or methylprednisolone) to treat prostate cancer that has spread to other parts of the body. Abiraterone is used in men with prostate cancer that cannot be treated with surgery or other drugs.
Abiraterone is not intended for use by women or children.
To make sure Abiraterone is safe, tell your doctor if you have ever had:
Liver disease Diabetes Heart problems High blood pressure A heart attack Low blood potassium Adrenal gland problems or your pituitary gland. Women who are pregnant or may become pregnant should not take the medicine, as it can be absorbed through the skin and harm the unborn baby. Abiraterone can also harm an unborn baby if the father is taking it at the time of conception.
So you need to use birth control during treatment with Abiraterone and for at least 3 weeks after your last dose.
2. How to use Abiraterone?
Use Abiraterone exactly as prescribed by your doctor. Abiraterone is usually taken once daily while also taking steroid medication 1 or 2 times daily.
Take Abiraterone with a full glass of water. Swallow the tablet whole and do not crush, chew, or break the tablet. Do not eat anything for at least 2 hours before or 1 hour after you take Abiraterone.
You will need to have your blood pressure checked regularly and may need frequent blood tests. If you have diabetes, your blood sugar should be checked carefully, especially if you take the medicine pioglitazone or repaglinide.
You should not stop taking Abiraterone or steroids suddenly, but reduce your dose of prednisone as directed by your doctor. The usual adult dose of Abiraterone for the treatment of metastatic or high-risk prostate cancer: 1000 mg orally once daily in combination with methylprednisolone 5 mg orally twice daily. In case of infection, use Abiraterone at a dose of 500mg orally once daily in combination with methylprednisolone 4mg, orally twice a day.
If you forget a dose of Abiraterone, skip the missed dose and take it the next day, do not take two doses at the same time. You should call your doctor for instructions if you miss more than one dose of abiraterone.
3. Side effects of the drug Abiraterone
If you have signs of an allergic reaction to abiraterone get medical help right away: Hives , trouble breathing; swelling of the face, lips, tongue, or throat.
Call your doctor if you experience the following side effects of Abiraterone:
Swelling in your ankles or feet, foot pain. Fast or irregular heartbeat. It feels like you might faint. Severe headache, blurred vision, pounding pulse in the neck or ears. Pain or burning when you urinate. Anemia manifests as pale skin, fatigue, feeling light-headed or short of breath, and cold hands and feet. Low blood potassium causes symptoms such as leg cramps, constipation, irregular heartbeat, fluttering in the chest, increased thirst or increased urination, numbness or tingling, muscle weakness or a limp feeling . Liver problems--stomach pain with symptoms such as nausea, vomiting, dark urine, yellowing of the skin or eyes. Low blood sugar with symptoms such as headache, hunger, sweating, irritability, dizziness, fast heartbeat, and feeling anxious or shaky. Common side effects of Abiraterone include:
Feeling very weak or tired Feeling very hot High blood sugar High blood pressure Swelling in the legs or feet. Anemia, hypokalemia. Painful urination Abnormal liver function tests. Joint pain or swelling. Headache . Nausea, vomiting, diarrhea. Cold symptoms such as sneezing, stuffy nose, cough, sore throat.
4. Interactions of Abiraterone with other drugs
Tell your doctor about all the medicines you are taking. Many drugs can interact with abiraterone, especially:
Other prostate cancer drugs, especially radium Ra 223, when used in combination with Abiraterone may increase the risk of fracture. skeletal. The drug pioglitazone or repaglinide in the treatment of diabetes when used with Abiraterone can cause severe low blood sugar. Knowing the information and medication process will bring the best treatment effect to the patient.
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