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Solumedrol drug with the main ingredient is Methylprednisolone 40mg, has anti-inflammatory and immunosuppressive effects. Solumedrol 40mg is used in certain cases such as cancer patients undergoing chemotherapy with nausea, vomiting... Depending on the situation, the dose of Solumedrol 40mg in each person will be different.
1. What are the effects of Solumedrol 40mg?
Solumedrol medicine 40mg has the main ingredient is Methylprednisolone with a strength of 40mg. The drug is prepared in the form of a powder and a liquid solution to dissolve the powder, administered by injection. Solumedrol 40mg drug has anti-inflammatory or immunosuppressive effects, used in the treatment of the following cases:
Adjuvant when the patient's life is threatened. Disorders when the disease is in the exacerbation phase or does not respond to standard treatment, including rheumatoid arthritis, polymyositis, multiple sclerosis, lupus erythematosus, glomerulonephritis. End stage cancer patient. Anti-nausea and vomiting in cancer patients undergoing chemotherapy. Acute spinal cord injury. Pneumocystis carinii pneumonia in AIDS patients. Chronic obstructive pulmonary disease in exacerbations.
Solumedrol 40mg có tác dụng chống viêm hoặc ức chế miễn dịch
2. Dosage of Solumedrol 40mg
Dosage of Solumedrol 40mg for each specific case of treatment is as follows:
Adjuvant when life-threatening: Intravenous 30mg/kg body weight for a minimum of 30 minutes. Repeat injection every 4-6 hours for 48 hours. Rheumatic disorders: 1g/day intravenously over a period of 1-4 days or 1g/month for a period of 6 months. A booster dose is given in case of 1 week post-treatment without improvement or as requested by the patient. Systemic lupus erythematosus: 1g intravenously/day for 3 days for a minimum of 30 minutes. Repeated dose of Solumedrol was performed in the event of 1 week post-treatment without improvement or as requested by the patient. Multiple sclerosis: Intravenous 1g/day for at least 30 minutes for about 3 or 5 days. A booster dose is given in case of 1 week post-treatment without improvement or as requested by the patient. Glomerulonephritis, edematous lupus nephritis: 30mg/kg body weight intravenously every 2 days for a period of 4 days or 1g/day for about 3.5 or 7 days. Repeated dose of Solumedrol was performed in the event of 1 week post-treatment without improvement or as requested by the patient. End stage cancer: Intravenous 125mg/day for 8 weeks. Prevention of nausea and vomiting in cancer patients undergoing chemotherapy: Intravenous injection of Solumedrol 250mg at least 5 minutes before chemotherapy 1 hour. When starting or stopping chemotherapy, the dose of Solumedrol should be repeated. To increase the antiemetic effect, the first dose can be combined with a chlorine derivative of phenothiazines. Treatment of acute spinal cord injury: Treatment is best given within 8 hours of illness. For patients starting treatment within 3 hours of illness: 30mg/kg body weight intravenously over 15 minutes, 45 minutes rest, then 5.4mg/kg body weight/hour continuous intravenous infusion for 23 hours in patients Patients were treated during the first 3 hours or an intravenous infusion of 5.4 mg/kg body weight/hour for 47 hours in patients treated for 3 to 8 hours. AIDS patients with Pneumocystis carinii pneumonia: Solumedrol 40mg IV every 6-12 hours for 72 hours up to a maximum of 21 days or the end of pneumocystis treatment. In addition, additional use of anti-tuberculosis drugs and monitoring for infection should be considered. Chronic obstructive pulmonary disease (exacerbations): Intravenous 0.5mg/kg body weight over 6 hours and administered for 72 hours; or 125mg IV every 6 hours for 72 hours but then switch to oral corticosteroids at a tapering dose. The minimum duration of treatment with Solumedrol is 2 weeks. Solumedrol 40mg is used intravenously, after dilution with isotonic saline solution or 5% dextrose, during the infusion process must always be monitored and supervised by a doctor or medical staff to prevent any adverse effects. Side effects will decrease the transmission rate. In addition, Solumedrol can also be administered intravenously or intramuscularly but slowly.
3. Side effects when taking Solumedrol 40mg
Solumedrol side effects can happen at any time, for a long or short time. The drug causes disorders in the immune system, endocrine system, metabolism, nutrition, mental health, nervous system, eye, cardiovascular, respiratory, digestive, skin, skeletal muscle and connective tissue, biology. fertility, general disorders.
Some unwanted effects of Solumedrol 40mg may appear during or after injection such as:
Blood pressure, heart rate changes; Increased blood sugar ; Electrolyte imbalance; skin flushing, sweating, trouble sleeping, convulsions; The mouth has a metallic taste; Mental disorders, changes in mood and behavior; Infection or anaphylaxis . Some undesirable effects appear for a long time such as acne, weight gain, stretch marks, thin skin, increased blood fat and blood sugar, cataracts, glaucoma, decreased bone density and increased risk. bone necrosis, myasthenia gravis, infection, growth inhibition.
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4. Notes when taking Solumedrol 40mg
Solumedrol is contraindicated in people with systemic fungal infections and allergic to its components. Tell your doctor about your medical history and current health status. Tell your doctor before doing the test because Solumedrol 40mg can falsify the results. Do not administer immunosuppressive drugs with attenuated or live vaccines. Solumedrol should not be used concurrently with certain vaccines, so any recent vaccinations should be reported. Solumedrol may interact with or change the effects of certain medications, such as nonsteroidal anti-inflammatory drugs, neuromuscular blocking drugs, treatment for tuberculosis, HIV, antibiotics, antifungals, treatment for high blood pressure, heart disease, diuretics, birth control, Alzheimer's treatment, glaucoma, myasthenia gravis, mental or anxiety disorders, bronchiectasis, immunosuppression, hormone disorder treatment, breast cancer. Pregnant women should only take Solumedrol 40mg if necessary, if used for a long time, it can cause hormone problems in the baby. Therefore, if after birth, the baby shows signs of nausea, vomiting, diarrhea, body weakness. In the elderly (over 65 years of age), treatment with Solumedrol may increase the risk of weakness and fractures, and increased blood pressure due to fluid retention. Provide information about current medications, including prescription and non-prescription drugs, dietary supplements, and herbs. The dose of Solumedrol 40mg depends on the individual treatment. Patients need to use the drug exactly as prescribed by the doctor or pharmacist to ensure the safety and effectiveness of treatment.
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