Causes of thrombocytopenia in people infected with dengue fever

This is an automatically translated article.


Article written by Doctor Le Xuan Luat - Vinmec Times City International General Hospital

Dengue hemorrhagic fever (DHF) is a disease transmitted by mosquito bites, common worldwide. The disease is present in many places such as Asia, Africa, and America. More than 100 countries are affected annually by Dengue hemorrhagic fever. The first case of dengue was recorded in Vietnam in 1960.

1. General situation of dengue hemorrhagic fever


Currently, Dengue hemorrhagic fever is a disease appearing in most provinces of Vietnam. The Central Highlands and the South are hot spots with the number of dengue cases increasing every year.
According to the World Health Organization, the number of dengue infections in Vietnam has increased over the years, the rate of increase of infections in each year is different. In 2009, the number of dengue infections was 102 people/100,000 people. In 2017, this number increased to 194 people infected with dengue per 100,000 population, an estimated 184,000 people infected with dengue.

Sốt xuất huyết Dengue là một bệnh lây nhiễm nhanh chóng tại nước ta
Sốt xuất huyết Dengue là một bệnh lây nhiễm nhanh chóng tại nước ta

2. Common clinical symptoms of SHXD


People infected with dengue often have clinical symptoms such as:
High fever, continuous fever, fever can last 3-7 days. Muscle fatigue Pain in both eye sockets Headache, possible severe headache Nausea, vomiting Red eyes Bleeding gums, nosebleeds More severe can bleed from the gastrointestinal tract, causing black stools, or discharge cerebral blood. >>> How many types of dengue virus cause hemorrhagic fever?

Trẻ bị sốt xuất huyết Dengue sẽ có biểu hiện sốt cao
Trẻ bị sốt xuất huyết Dengue sẽ có biểu hiện sốt cao

3. Thrombocytopenia in dengue


The most common laboratory sign in people with dengue infection is a low platelet count. Platelets are a component in the blood, playing an important role in the clotting system, forming blood clots, and reducing bleeding. When platelets decrease in blood count, the risk of bleeding in people with dengue infection increases.
The number of platelets may decrease from the 2nd day of fever, much less from the 4th to 6th day of fever. Platelet counts usually recover by day 7 of fever.
The decrease in the number of platelets in the blood is explained by:
The aggregation of platelets The platelets are resolved The platelets are phagocytosed. Bone marrow suppression Therefore, when having a fever during the epidemic season, people should Go to health facilities to check if you have dengue infection or not? If you are infected with dengue, you will need medical advice on monitoring and treatment.
>>> 3 tests to find the cause of dengue fever
Dengue diagnostic test helps determine the presence of the virus that causes the disease in the blood. Tests commonly used to diagnose dengue are NS1, IgM antibodies, and IgG antibodies.
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