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Question
Hello doctor,
I have hepatitis B, the blood test index is AST=47; ALT=56;GGT=32; HBsAg=6427; HBcrAg=4.3.
I would like to ask the doctor if the hepatitis B test results can tell if the virus is sleeping or active? Do I need a viral load test? Thank you doctor!
Tran Kim Quan (1971)
Reply
Hello,
To the question "Can hepatitis B test results conclude that the virus is sleeping or active?", the doctor would like to answer as follows:
HBcrAg is a core-associated antigen of the hepatitis B virus, thought to be a novel biomarker that plays an important role in chronic hepatitis B because of its correlation with serum HBV-DNA and cccDNA levels. in the liver. Currently, this marker is used in monitoring the treatment of hepatitis B. However, to conclude whether the virus is dormant or active, current regimens do not include this criterion for diagnosis. Current diagnostic criteria are still based on: liver enzymes, HBV-DNA, HBeAg and degree of liver fibrosis. Therefore, you still need to do other tests to diagnose the stage.
If you still have questions about the diagnosis of hepatitis B virus, you can go to a hospital under Vinmec Health System for further examination and advice. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
Best regards!
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
Answered by Resident Doctor, Doctor Nguyen Thi Thuy Hang - Doctor of Microbiology - Laboratory Department - Vinmec Times City International General Hospital.
