Biliary tract infection

This is an automatically translated article.

The article was written by TS. Vu Tan Phuc - Gastroenterologist - Department of Medical Examination & Internal Medicine - Vinmec Phu Quoc International General Hospital

Biliary tract infection is one of the diseases with high mortality because the disease progresses rapidly, causing sepsis. What are the causes, symptoms and treatment?

Biliary tract infection is an inflammation of the biliary tract mainly caused by bacteria, usually occurring in patients with biliary obstruction. If not treated promptly, the disease can turn to sepsis, with a high mortality rate, especially in elderly patients with many underlying diseases. Biliary tract infections causing sepsis most commonly occur in patients with underlying structural abnormalities, usually cholelithiasis or malignancy. The main causes of biliary tract infections include:
Bacteria: mainly intestinal bacteria. The most common pathogens are usually gram-negative bacteria, among which are Escherichia coli, Klebsiella pneumoniae, . . . The causes of biliary tract narrowing and obstruction: gallstones, worms in the bile ducts, cholangiocarcinoma, ampulla of Vater, pancreatic head tumor, sphincter of Oddi, . . . Bile duct abnormalities.

Nhiễm trùng đường ruột chủ yếu do vi khuẩn gây ra
Nhiễm trùng đường ruột chủ yếu do vi khuẩn gây ra

1. Diagnosis of biliary tract infection


The most typical clinical symptom is the Charcot triad: right upper quadrant pain, fever, and jaundice. However, only one-third of patients have all of the above symptoms.
In addition, patients also experience some accompanying symptoms such as nausea, digestive disorders, loss of appetite. . . Therefore, the diagnosis is often based on signs such as abdominal pain, jaundice combined with laboratory support such as increased CRP, leukocytosis, abnormal liver function, CT scan or MRI presence of obstruction.

Nhiễm trùng đường mật có thể kèm theo rối loạn tiêu hóa
Nhiễm trùng đường mật có thể kèm theo rối loạn tiêu hóa

2. Treatment of biliary tract infections


Must be very urgent because biliary tract infection is very easy to turn into sepsis, septic shock, very high mortality. Antibiotic selection is the key to success in treatment: it is necessary to combine antibiotics, with a spectrum of activity targeting intestinal gram-negative bacteria, mainly E. coli. Biliary re-circulation is the key issue for treatment as well as prevention: endoscopic retrograde cholangiopancreatography (ERCP), stone removal, worm removal, biliary stenting, surgery. . . Active resuscitation in shock: vasopressor, oxygen, water and electrolyte balance, acid-base. Sometimes a combination of resuscitation and biliary revascularization is required.

Điều trị nhiễm trùng đường mật bằng phương pháp nội soi ngược dòng
Điều trị nhiễm trùng đường mật bằng phương pháp nội soi ngược dòng

Biliary tract infection is a dangerous disease, so you should check your health regularly for early detection and timely treatment, to avoid the disease turning into sepsis. Vinmec International General Hospital has general health checkup packages suitable for each age, gender and individual needs of customers with a reasonable price policy, including:
Kim's general health checkup package outline Vip General Health Checkup Package Special General Health Checkup Package Comprehensive General Health Checkup Package Standard General Health Checkup Package Patient's examination results will be returned to your home. After receiving the results of the general health examination, if you detect diseases that require intensive examination and treatment, you can use services from other specialties right at the Hospital with quality treatment and services. outstanding customer service.
Customers can call the hotline or register for an online consultation with Vinmec HERE.
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