Bebulin drug: Uses, indications and notes when using

This is an automatically translated article.

Factor IX is a natural protein in the blood that helps blood to clot. A lack of clotting factors can cause uncontrolled bleeding, because the blood cannot clot properly. Bebulin is used to treat or prevent bleeding episodes in people with factor IX deficiency (hemophilia B). It is also used to control bleeding associated with surgery or dentistry in people with hemophilia B.

1. Uses of the drug Bebulin

Bebulin is used to prevent or control bleeding in people with little or no factor IX (due to hemophilia B, Christmas disease). Factor IX is a protein (clotting factor) in the blood that works with other clotting factors to help the blood clot and thereby help stop bleeding. People with little or no factor IX, are at increased risk of bleeding for longer after injury/surgery or sudden bleeding (usually in a joint/muscle) with no known cause.
Most of these drugs should not be used to treat other forms of factor deficiency (eg, factor II, VII, VIII, X) or factor problems (eg, inhibitors factor XIII). If you are using medication for one of these conditions, consult your doctor or pharmacist to make sure you are using the correct product.

2. How to use Bebulin Vial

The drug is injected into a vein as directed by your doctor. Dosage is based on each patient's medical condition (such as extent and location of bleeding), weight, and response to treatment.
Turn the vial gently so that the medicine mixes well. Some forms of medication must be completely mixed into the liquid to form a solution that does not contain particles. In this case, do not use the solution if it contains particles. However, with other forms of this medicine there can sometimes be some small particles in the vial, even when the medicine is mixed correctly. In these cases, the particles will not affect how well the drug works. If you have questions about whether this form of medicine can be used if it contains particles or if you have other questions about its use, consult your doctor or pharmacist. The medicine in the bottle and the items that come with the medicine should only be used once. Do not reuse. Throw away after one use, even if there is still some medicine left after injecting your dose.
After mixing, shake the mixture gently and let the medicine dissolve completely. Use the medicine as soon as possible after reconstitution. You can store the reconstituted medication at room temperature, but it must be used up within 3 hours. Do not put the mixed medicine in the refrigerator.
A single dose of factor IX may be sufficient to control minor bleeding. If a second dose is needed, wait at least 24 hours before using it again.
Check pulse before and during injection. If pulse rate changes, stop injection until pulse rate returns to normal.

3. Bebulin side effects

One of the side effects of Bebulin is possible pain at the injection site, chills, tingling, flushing, headache, nausea or vomiting.
Tell your doctor if you have any serious side effects, including: swelling at the injection site, fast heartbeat, trouble breathing, signs of kidney problems (such as change in the amount of urine) , swollen ankles/feet, pain/redness/swelling of hands or feet, new or worsening bleeding/bruising. Get medical help right away if any of these rare side effects occur: chest pain, trouble breathing, bluish fingers.
Bebulin is made from human blood. Although the donors are carefully screened and the medicine has gone through a rigorous manufacturing process, there is still a very small chance that you could develop a drug-related infection (including hepatitis virus infection). ). Also tell your doctor if you have any signs of hepatitis or other infection, including fever, persistent sore throat, unusual tiredness, nausea, persistent vomiting, yellowing eyes, skin, dark urine.

4. Be careful when using Bebulin

Before using factor IX, tell your doctor or pharmacist if you are allergic to factor IX products or have any other allergies. This product also contains excipients that may cause allergic reactions or other problems.
Before using this medicine, tell your doctor or pharmacist your medical history, especially of: other blood clotting disorders (e.g. disseminated intravascular coagulation -DIC), heart disease (e.g., disseminated intravascular coagulation -DIC). , coronary artery disease ), immune system problems, recent surgery or procedure, liver disease. If you need to have any type of surgery or dental procedure, tell the surgeon or dentist in advance that you have hemophilia.
Bebulin is not approved for use by anyone under the age of 18. Since the medicine is made from human blood, there is a very small chance of getting an infection from it (including viral infections such as hepatitis).
It is important to take the correct and full dose of this medication on schedule. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Do not take a double dose to make up for a missed dose. Because your body can develop antibodies or "inhibitors" to Bebulin. As the body develops "inhibitors" of the clotting factor, this treatment becomes less effective at preventing bleeding episodes. Call your doctor if the medicine seems to be less effective in controlling bleeding.

5. Possible Bebulin drug interactions

Drug interactions can change the effectiveness of medication or increase the risk of serious side effects. Some drugs that may interact with this drug include: blood clotting drugs (aminocaproic acid, tranexamic acid).
Remember, always keep medication out of reach of children, never share your medication with others, and use it only as directed. Always consult a medical professional to ensure that the information displayed on this page is appropriate for your individual situation.
The use of drugs for the right purpose always brings high efficiency and positive effects to the patient's health. Therefore, before using, it is necessary to carefully read the instructions for use and consult a qualified person.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.

Reference source: webmd.com - drugs.com