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The article was professionally consulted by Dr. To Minh Huong - Head of Clinical Reproductive Support Unit - Reproductive Support Center - Vinmec Times City International HospitalEstablished in November 2014, 4 years of operation now, Vinmec IVF fertility center has provided fertility support to more than 1000 infertile couples with the clinical pregnancy rate always reaching over 40%. This rate is equivalent to developed countries such as the US, UK, Australia... The following article will help families better know about assisted reproductive techniques performed at Vinmec.
1. Intra-cytoplasmic sperm injection (ICSI)
Used for the most common male infertility cases are low sperm count and poor sperm quality or sperm removed from the epididymis or testicles. Cases of unknown cause or elderly women > 40...At that time, the method of injecting sperm into the oocyte is performed to increase the possibility of fertilization. A good quality sperm is selected for direct injection into the cytoplasm of the egg. After successful fertilization, the embryos will be cultured until the 3rd or 5th day, then transferred back to the woman's uterus for implantation.
2. Assisted hatching (AH)
The technique of supporting embryo drainage is the manipulation of thinning or opening the outer membrane of the embryo, increasing the ability of the embryo to adhere to the uterine lining, thereby increasing the ability of the embryo to implant. Studies have demonstrated that the AH technique increases pregnancy rates in women >38 years of age and in frozen embryo transfers.3. Embryo transfer at the blastocyst stage (embryo day 5) A natural pregnancy cycle, day 5 embryos arrive in the uterus and begin to implant. Therefore, the purpose of embryo transfer at the blastocyst stage (day 5 after egg retrieval) is to increase implantation, increase pregnancy rate, and limit the risk of multiple pregnancies due to the number of embryos to be transferred. less than the number of embryos transferred on day 2 or 3. However, raising embryos on day 5 must be supported by modern equipment and closely monitored by doctors.
At Vinmec Fertility Center, by operating the advanced mini-incubator culture cabinet system from the very beginning with a team of experienced experts, day 5 embryo culture and transfer has closed. contributed greatly to increase the success rate of IVF at the center to the same level as leading centers in Vietnam and the world.
4. Cryopreservation of embryos, sperm and oocytes 4.1. Embryo freezing Remaining embryos after being transferred to the uterus will be frozen for a long time, if the cycle of fresh embryo transfer does not yield results or the couple wants to have more children, they will conduct frozen embryo transfer without any results. There is no need to undergo ovarian stimulation. In addition, in cases of ovarian hyperstimulation, the whole embryo freezing and the next cycle of embryo transfer will avoid complications and increase the possibility of pregnancy.
4.2. Sperm cryopreservation Sperm cryopreservation is applied to men before cancer treatment or treatments that may affect fertility, or in case their husbands are away from home. . Sperm have good viability after thawing if properly refrigerated.
4.3. Frozen oocytes Long-term cryopreservation helps preserve fertility in women undergoing cancer treatment or in women who wish to delay childbearing. Vinmec Fertility Center is currently applying the most effective cold storage method at major fertility centers around the world, which is vitrification.
5. In vitro maturation method (IVM) After oocyte aspiration, immature oocytes can be further cultured in the IVF lab for about 24 – 48 hours to reach a mature state. Fort. Only mature ovules are able to fertilize the sperm and develop into an embryo.
IVM technique has been shown to be very effective in cases of polycystic ovaries, history of ovarian hyperstimulation, history of poor quality oocytes (eggs).
6. Surgical sperm collection in case of male infertility In cases of male infertility, there is no sperm in the semen due to blockage of the vas deferens even though the testicles still produce normal sperm. The most common treatment for obstructive azoospermia in the world today is surgical sperm collection and ICSI (cytoplasmic sperm injection). The methods of surgical sperm collection currently being applied at many prestigious IVF centers around the world and at Vinmec IVF Center are:
Percutaneous epididymal sperm collection (PESA) aspiration), Microsurgical epididymal sperm aspiration (MESA), Testicular sperm aspiration (TESA), which includes testicular aspiration testicular fine needle aspiration (TEFNA) Removal of sperm from the testicle by surgical testicular sperm extraction (TESE). The sperm obtained after the procedure will be fertilized with the ovum by intracytoplasmic sperm injection (ICSI) technique. The pregnancy rate of this treatment is similar to that of conventional ICSI.
7. Oocyte, sperm and embryo donation Vinmec Fertility Center also provides oocyte, sperm and embryo donation services for infertile couples who do not have ovules, sperm and embryos due to certain factors. pathology: premature ovarian failure, testicular failure... Infertility specialists at the Center will consult in detail on each specific case, in order to obtain optimal results for the couple.
Eggs, sperm, embryos are carefully stored, ready to meet the needs of couples
8. Other services at Vinmec IVF Reproductive Center Semen analysis and sperm washing for Intrauterine insemination Surgery related to infertility treatment Treatment of endocrine-related disorders Treatment of male endocrine disorders These assisted reproductive techniques are currently being applied at most of the large, reputable assisted reproductive centers around the world.
If you need more advice about reproductive health and your own case at IVF Vinmec Fertility Center, do not hesitate to come directly to the consultation or contact the website for support.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.