Amiloride HCL: Uses, indications and precautions when using

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Diuretics are one of the first choices when treating high blood pressure, heart failure, or edema. There are many different classes of diuretics, including Amiloride HCL. So what is amiloride HCL?

1. What disease does amiloride HCL treat?

What is Amiloride HCL? Amiloride HCL belongs to a group of diuretics (including drugs such as furosemide loop diuretics, thiazide diuretics such as hydrochlorothiazide) used to treat high blood pressure, heart failure, or fluid overload in the body (causing edema).
Amiloride HCL is also used to treat or prevent hypokalemia as a side effect of other diuretics. Because the drug is used to treat high blood pressure, it is effective in preventing stroke, heart attack and kidney diseases.
Amiloride HCL is a potassium-sparing diuretic, both eliminating fluid and salt, and preventing the elimination of potassium from the body.

2.How to use Amiloride HCL

Amiloride HCL is used by mouth, taken after meals, usually once a day or as directed by a doctor.
If amiloride HCL is taken near bedtime, the patient may have sleep disruptions to urinate at night. Therefore, it is best for patients to take this medication at least 4 hours before bedtime. If you have any questions about how and when to take amiloride HCL, consult your doctor or pharmacist.

The dose of amiloride HCL diuretic depends on the patient's health status and response to treatment.
Need to use amiloride HCL regularly, regularly to bring the highest effectiveness. Patients should take their medication at the same time each day to remember and should continue taking amiloride HCL even if the patient feels better.
Patients should consult their doctor if treatment of high blood pressure with Amiloride is not effective (eg, blood pressure readings remain high or elevated).

3. Side effects of amiloride HCL

Possible side effects when taking amiloride HCL include:
Headache; Dizzy ; Nausea, vomiting; Loss of appetite, stomach or abdominal pain, bloating or diarrhea. When patients need to take amiloride HCL with other diuretics, excessive loss of water, salt, and electrolytes from the body can occur. Notify the doctor immediately when the patient shows signs of dehydration or severe dehydration such as:
Dry mouth; Thirst a lot; Muscle spasticity;

Weak body ; heart palpitations; Severe dizziness, confusion, fainting, or seizures. In addition, some rare but serious side effects may occur such as:
Signs of kidney problems such as changes in the amount of urine; Yellow eyes, yellow skin; Dark urine ; Prolonged nausea and vomiting. Very rarely, amiloride HCL causes serious allergic reactions.

4.Precautions when using amiloride HCL

Physicians should investigate allergies to amiloride or any other history of allergies before prescribing this diuretic.
Before treating high blood pressure with amiloride, patients should discuss with their doctor about their previous medical history, especially:
Untreated water and electrolyte imbalance such as high blood potassium, blood sodium low Kidney disease, liver disease; Diabetes mellitus; Dehydration.

The drug amiloride HCL has side effects causing dizziness. Concomitant use of alcohol or drugs will make the condition worse. In particular, patients with dizziness absolutely do not drive, operate machinery or do things that require alertness until the dizziness is gone. If the patient is using drugs, the patient should inform the treating physician.
Dehydration can be aggravated by excessive sweating, vomiting or loose stools, which can lead to a drop in blood pressure and worsen dizziness. Therefore, patients need to drink plenty of fluids to prevent these side effects and limit dehydration. If the patient needs to limit fluid intake, consult a doctor for exact instructions.
Amiloride HCL is a potassium-sparing diuretic, so blood potassium levels may increase, so patients need to limit eating foods rich in potassium ions such as bananas, oranges...
Women during pregnancy Pregnant women should only use amiloride HCL when clearly needed and need to discuss with their doctor the benefits and risks of taking the drug.
It is not known whether amiloride HCL passes into breast milk. Therefore, patients who are breastfeeding should consult their doctor about the side effects of the drug before taking it.

5.Amiloride HCL drug interactions

Drug interactions that change the main effect and increase the risk of serious side effects. Patients should talk to their physician about all products they are taking to prevent drug interactions. Do not start, stop or change the dosage of amiloride HCL without your doctor's consent.
Some products may interact with this drug:
Lithium; Products containing sodium phosphate; Other drugs that may increase blood potassium levels such as eplerenone, tacrolimus, cyclosporine, oral contraceptives containing drospirenone, other potassium-sparing diuretics such as spironolactone and triamterene, ACE inhibitors such as benazepril, captopril, receptor antagonists angiotensin bodies such as losartan and valsartan.

Some medications for other medical conditions contain ingredients that increase blood pressure or worsen heart failure, so consult your pharmacist on how to use them safely. safety (especially cough and cold medicines, diet aids, non-steroidal anti-inflammatory drugs such as ibuprofen, naproxen).
Amiloride HCL may affect the results of some tests (including glucose tolerance tests). Signs of overdose with this diuretic include fainting, trouble breathing, severe dizziness, slow or irregular heartbeat.
After using the drug, patients need to have periodic health check-ups, perform tests such as kidney function tests, electrolyte levels such as potassium ... to monitor disease progression or detect disease. side effects. In addition, patients also need to check and measure blood pressure regularly while using amiloride HCL, especially when using it for the first time or when changing dosage. If the patient forgets a dose, take it as soon as he remembers. If you miss a dose when it is almost time for the next dose, do not take a double dose to make up for it, to avoid poisoning from an overdose.
Amiloride HCL is a diuretic, indicated for the treatment of high blood pressure, heart failure or fluid overload in the body (causing edema). For the drug to work best, patients need to follow the instructions of the doctor or pharmacist.

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Reference source: webmd.com