Afstyla: Uses, indications and precautions when using

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Afstyla is used to control and stop bleeding episodes in people with low levels of factor VIII (hemophilia A). This medication is also used in these patients before surgery to prevent bleeding.

1. How to use Afstyla Vial


Afstyla is given by injection into a vein as directed by your doctor. The medicine may need to be injected more slowly for a longer time depending on the dose and how the person responds to the medicine.
Afstyla is used in people with low factor VIII who are at risk of bleeding for longer after injury/surgery and bleeding inside the body (especially into joints and muscles). This product contains a man-made form of factor VIII, which is used to temporarily replace the missing factor VIII, a protein (clotting factor) normally found in the blood for the purpose of treating and preventing bleeding. .
This medicine should not be used to treat von Willebrand disease (a bleeding disorder).
After first receiving this medication at a treatment center or hospital, some patients are able to self-administer it at home. If your doctor directs you to use this medicine at home, read your doctor's instructions for use carefully before you start using this medicine and each time you get it back. Learn how to safely store and dispose of needles and medical supplies. If you have any questions, ask your healthcare professional.
If the medicine and solution can be refrigerated, let both come to room temperature before combining. After adding the solution to the powder, gently stir the mixture until the powder is completely dissolved. Don't shake. Before using this product, visually inspect for particles or discoloration. If yes, do not use liquid. Use immediately according to product instructions.
Dosage is based on your medical condition, weight, blood test results and response to treatment. Follow your doctor's instructions exactly.
Tell your doctor if your condition does not improve or if it becomes progressively worse.

Thuốc này không nên được sử dụng để điều trị bệnh von Willebrand
Thuốc này không nên được sử dụng để điều trị bệnh von Willebrand

2. Side effects


Using Afstyla can sometimes occur some side effects such as flushing, headache, nausea and heart palpitations. These symptoms may be alleviated by injecting this medicine more slowly. In addition, the patient may also experience burning/redness/irritation at the injection site, fever, and chills. If any of these side effects persist or get worse, tell your doctor or pharmacist right away.
Your doctor decided to prescribe this medication to you because he or she has judged that the benefit to you outweighs the risk of side effects. Many people who use this medicine have no serious side effects.
Afstyla rarely causes serious side effects. However, seek immediate medical attention if you notice any of the following symptoms, including: Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, chest tightness/tightness.
Unwanted effects not listed above may occur. Therefore, if you notice any unusual symptoms after the injection, please contact your doctor immediately for timely treatment.

3. Precautionary measures


Before using Afstyla, if you are allergic to any product with factor VIII or any other allergies, tell your doctor or pharmacist immediately. Some brands may also contain polyethylene glycol (PEG), or inactive ingredients (such as natural rubber/latex) that can cause allergic drug reactions or other problems. For more information, contact your treating physician.
You need to provide your complete medical history before using this medicine.
The manufacturers of some brands of these drugs recommend that patients monitor their heart rate during treatment. If the heart begins to beat faster, the person may need to slow down the injection or temporarily stop the infusion until the heart rate returns to normal.
Women during pregnancy should only use this drug in case of absolute necessity. Discuss the risks and benefits you will receive with your treating doctor.
It is not known whether Afstyla affects breast milk in any way, so women who are breastfeeding should consult their doctor before using this medicine.

Phụ nữ trong thời kỳ mang thai chỉ nên sử dụng loại thuốc này trong trường hợp thật sự cần thiết
Phụ nữ trong thời kỳ mang thai chỉ nên sử dụng loại thuốc này trong trường hợp thật sự cần thiết

4. Drug interactions


Before checking with your doctor or pharmacist, never start, stop or change the dose of any medicine.
Name all herbal products, prescription and over-the-counter medicines you are taking to your doctor or pharmacist before using this medicine.
If you have overdosed and develop serious symptoms such as fainting or difficulty breathing, contact an emergency center immediately.
Laboratory blood tests (eg, factor VIII levels) should be performed regularly to determine the dose of the drug you are taking and to check how well it is working.
It's important to get the most out of your medication by following the dosing schedule as directed by your doctor. If you miss a dose, contact your doctor to set up a new dosing schedule. Don't use a double dose to catch up.
Afstyla should be stored according to the manufacturer's instructions. Protect the product from light. After reconstitution, use the product within the time frame stated in the manufacturer's instructions and discard the unused portion. Keep out of reach of children.
Unless instructed to do so, do not attempt to flush medication down the toilet or down the drain. Dispose of this product properly when it has expired or is no longer needed. Discard the needle in a needle cartridge. Do not reuse the needle in future uses.
If stored at room temperature, throw away any unused vials 3 months or after the expiration date, whichever comes first.

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Reference source: webmd.com
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