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Seebri breezhaler is commonly used to treat the symptoms of chronic obstructive pulmonary disease in adults. In addition, doctors often recommend the use of Seebri breezhaler to help people with shortness of breath feel easier to breathe, and effectively relieve chronic cough or chest pain. During the process of taking Seebri breezhaler, the patient needs to follow all the instructions of the doctor to get well soon.
1. What is Seebri breezhaler?
Seebri breezhaler belongs to the group of drugs acting on the respiratory tract, originating from Novartis Pharm Stein A.G - Switzerland, often recommended by doctors in the treatment of chronic obstructive pulmonary disease. Currently, the drug Seebri breezhaler is made in the form of inhalation powder contained in hard capsules, each box includes 3 blisters x 10 capsules with an inhaler device.
Each capsule contains Seebri breezhaler inhalation powder containing the main ingredient Glycopyrronium (as Glycopyrronium bromide) content of 50mcg. In addition to the above active ingredient, Seebri breezhaler also includes a number of other excipients that are just enough for one capsule.
2. What does Seebri breezhaler do?
2.3 Uses of the drug Seebri breezhaler The main active ingredient Glycopyrronium in the drug Seebri breezhaler is known as an anti-muscarinic agent, capable of competitively inhibiting the activity of Acetylcholine at Muscarinic receptors in the parasympathetic nervous system. In addition, Glycopyrronium is also a competitive inhibitor of Muscarinic cholinergic receptors in the salivary glands and other peripheral tissues. Thanks to this use, the rate of saliva secretion is significantly reduced. The active substance Glycopyrronium is eliminated mainly by the kidneys unchanged. Within the first 24 hours, approximately 65% of an intravenous dose of Glycopyrronium is eliminated by the kidneys and only about 5% is excreted in the bile. Depending on the route of administration, the half-life of Glycopyrronium will be different, specifically:
Intravenous administration: Elimination time is from 0.83 ± 0.27 hours. Intramuscular: Elimination time is 75 minutes. Oral solution: Elimination time is from 2.5 to 4 hours. 2.2 Indications for use of the drug Seebri breezhaler The drug Seebri breezhaler is often prescribed by doctors for maintenance treatment to help quickly relieve symptoms and exacerbations of chronic obstructive pulmonary disease (COPD). In addition, Seebri breezhaler is also used to positively improve patients with chronic cough, shortness of breath, cough with phlegm, chest pain or shortness of breath,...
2.3 Contraindication to using Seebri breezhaler Do not use Seebri breezhaler for the following cases:
People with hypersensitivity or allergy to the active ingredient Glycopyrronium or any of the excipients contained in the drug. Relative contraindications for pregnant women, mothers in the lactation period. Contraindicated in patients with severe renal impairment or end-stage renal disease requiring dialysis. Seebri breezhaler is contraindicated in children under 18 years of age.
3. Dosage and how to use Seebri breezhaler
3.1 Dosage of Seebri breezhaler as recommended The dose of Seebri breezhaler will be determined based on the medical condition of each patient. Usually, the dose of Seebri breezhaler will be 1 time / day.
3.2 How to properly and effectively use Seebri breezhaler The patient needs to strictly follow the doctor's instructions on the dose and how to use Seebri breezhaler to avoid harm to health. Here are the doctor's recommendations for the safe and effective use of Seebri breezhaler that patients should refer to:
Seebri breezhaler is inhaled through the mouth using the included inhaler. Seebri breezhaler should be inhaled at the same time each day to avoid missing doses. Never swallow capsules. If trot misses a dose of Seebri breezhaler, the patient needs to replenish the medicine as soon as possible. In addition, during the use of Seebri breezhaler, patients also need to avoid arbitrarily changing the dose, such as increasing, decreasing the dose or quitting halfway without approval from the doctor. This not only reduces the effectiveness of Seebri breezhaler but even increases the risk of side effects.
4. Possible side effects when using Seebri breezhaler
Here are some potential side effects during treatment with Seebri breezhaler , including:
Cough. Sore throat, throat irritation. Pharyngitis. Upper respiratory tract infection. Urinary tract infections. Rhinitis. Sinusitis . Headache or dizziness. Caries. Eat but can not digest. Fever. Chest pain. Musculoskeletal pain. When any of the above mentioned side effects occur during or after the use of Seebri breezhaler, the patient should discontinue the drug and notify the physician as soon as possible for appropriate management. Some side effects have the risk of complications and leave serious consequences for the patient's health if detected and treated late.
5. What patients should note when using Seebri breezhaler
5.1 What precautions should be taken while using Seebri breezhaler? During the use of Seebri breezhaler, patients should note some of the following recommendations:
Caution when using Seebri breezhaler for patients with coronary artery disease, urinary retention, arrhythmia, acute myocardial infarction, infection thyrotoxicosis, epilepsy, hypertension, diabetes or abnormal response to ß2-adrenergic agonists. Seebri breezhaler should be used with caution in patients being treated with tricyclic antidepressants, MAOIs, or drugs with the potential to prolong the QT interval. Seebri breezhaler is not recommended for use in patients under 18 years of age. Seebri breezhaler should not be used to treat asthma. Seebri breezhaler should be stopped immediately if signs of an allergic reaction (difficulty breathing, skin rash, hives, swelling of the face, swelling of the lips, swelling of the tongue or difficulty swallowing) occur; symptoms of acute angle closure glaucoma or paradoxical bronchospasm. Consider discontinuing Seebri breezhaler treatment in the presence of increased blood pressure or increased heart rate. Avoid using Seebri breezhaler inhaler in higher doses than recommended. Seebri breezhaler should only be used by pregnant women, nursing mothers, patients with renal failure or end-stage renal disease when the potential benefits outweigh the risks. Seebri breezhaler should be used with caution in patients whose jobs require frequent driving, operating machinery or working at height because the drug can cause side effects such as dizziness or headache. Store the medicine in the manufacturer's sealed packaging, avoid exposing it to direct sunlight and keep it out of reach of small children. 5.2 Seebri breezhaler can interact with which drugs? Some drugs, when used concurrently with Seebri breezhaler, may cause unintended interactions. This could lead to adverse effects on the effectiveness of the active ingredients in the medicine or increase the risk of serious side effects. Below is a list of drugs with potential for interactions when combined with Seebri breezhaler, including:
Other sympathomimetic drugs may increase the side effects of Indacaterol. Co-administration of Seebri breezhaler with methylxanthine derivatives, non-potassium-sparing diuretics or steroids may lead to hypokalemia. Muscarinic receptor antagonists or drugs containing Beta-adrenergic agonists may have an interaction reaction when used concomitantly with Seebri breezhaler. Eye drops when used concurrently with Seebri breezhaler may antagonize or reduce the effect of Beta2-adrenergic agonists. Some other anticholinergics also have the potential to interact with Seebri breezhaler. In order to minimize the interaction between Seebri breezhaler and other drugs, patients should inform their doctor about all the medicines they are currently taking, including vitamins, herbs or manufactured foods. from natural herbs. The doctor will base on the results of the risk assessment of drug interactions to advise on the most effective use of Seebri breezhaler.
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