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Psycholanz-10 is a psychotropic drug, containing the main ingredient is Olanzapine, 10mg strength, prepared in the form of film-coated tablets. The drug is used in the treatment of schizophrenia and psychotic disorders. To better understand the use of Psycholanz-10, please read the information in the article below.
1. What is Psycholanz?
What is Psycholanz? The drug psycholanz-10 contains the active ingredient Olanzapine, which belongs to the psychotropic group. Olanzapine is an antipsychotic, neuroleptic drug thanks to its mechanism of action due to its antagonism at serotonin receptors type 2, 3, 6 and dopamine in the central nervous system, inhibiting, reducing the response to 5HT2A receptor and antagonistic activity with muscarin receptors. In addition, olanzapine has anticholinergic effects, thereby reducing the risk of extrapyramidal syndrome. The effect of causing postural hypotension, drowsiness of the drug is related to olanzapine's antagonism of histamine H1 receptors and alpha-1 adrenergic receptors.
Olanzapine is well absorbed when administered orally, peak blood concentrations are achieved after 5 - 8 hours. Olanzapine is rapidly and extensively distributed into body tissues and central nervous system cells. The drug is metabolised in the liver and excreted by the kidneys in the urine mainly in the form of metabolites.
2. Indications and contraindications of Psycholanz-10
2.1. Indications The drug is prescribed for use in cases where the patient has the following symptoms: positive (paranoid, hallucinating, suspicious...), negative (apathy, withdrawal,... .) or suppression of psychotic disorders and schizophrenia.
2.2. Contraindications The drug is not contraindicated in patients with a history of allergy, hypersensitivity to olanzapine and excipients contained in the drug. The patient is suffering from narrow-angle glaucoma. Pregnant women and nursing mothers should not use the drug because the drug crosses the placenta and enters the infant's body through the amount of drug excreted in breast milk.
3. Dosage and how to use Psycholanz-10
How to use: The drug is used in oral form, the patient should take the drug in a single dose of the day, at the same time conventionally every day. You should take the tablet whole with a full glass of water, with or away from a meal.
Dosage: The drug is used according to the specific dosage instructions of the doctor on each patient, depending on the health condition and clinical course of the disease or you can refer to the manufacturer's recommended dose below. Here: Take a single dose every day from 5mg to 20mg.
Adults
Schizophrenia: The starting dose is 5 - 10 mg orally per day, increasing by 5 mg/day for the first week to a target dose of 10 mg/day. In the later stages, the dose may be adjusted at 5 mg/day at intervals of not less than 7 days up to a maximum dose of 20 mg/day. Maintenance dose: 10 to 20 mg once a day.
Treatment of mania:
Monotherapy: Starting dose at 10 -15 mg/time/day, gradually increasing dose by 5 mg/day, daily maintenance dose from 5 to 20 mg, highest recommended dose 20mg/day. Multitherapy: Starting dose is 10-15 mg/time/day, maximum 20mg/day. Children
Schizophrenia: The starting dose is 2.5 - 5 mg/time/day. The recommended dose is 10mg/day, up to a maximum of 20mg/day. Bipolar disease: Starting dose from 2.5 to 5 mg/time/day. The recommended dose is 10mg/day, the maximum dose is 20mg/day. In the elderly, patients with liver and kidney failure: The starting dose is 5mg/time/day.
4. Undesirable effects of Psycholanz-10
Undesirable side effects while using psychotropic drugs Psycholanz-10 can be clinically encountered with the following frequency:
Common: Weight gain and somnolence, hyperprolactinemia. Uncommon: Dizziness, increased appetite, peripheral edema, orthostatic hypotension, dry mouth and constipation, eosinophilia, elevated liver enzymes ALT and AST. Rare : Rash, photosensitivity reactions, hepatitis, seizures. In the process of using the drug, when any unwanted effects appear, the patient should stop taking the drug, contact the doctor/medical staff or go to the nearest medical facility for examination and advice. and prompt treatment.
5. Notes when using Psycholanz-10
Precautions when taking Psycholanz-10 are as follows:
Consider using Psycholanz-10 when you are taking: levomethadyl, metoclopramide, diazepam, CYP1A2 inducers (carbamazepine, phenytoin, rifampicin, phenobarbital.. .), fluvoxamine, , ciprofloxacin, caffeine, erythromycin, quinidine, dopamine, adrenaline, levodopa.... Therefore, you need to fully inform the medicine you are taking to the specialist to be prescribed correctly. Do not smoke and drink alcohol while using psychotropic drugs. You should take activated charcoal orally at least 2 hours before you take it. The drug should not be used in children under 13 years of age, because there are no clinical studies on safety and effectiveness. Elderly patients, patients with: heart disease, cerebrovascular disease, diabetes, impaired liver function, history of epilepsy should be closely monitored during the course of drug use. The drug has a sedative effect, affecting the ability to concentrate and move, so you should not directly drive or operate machinery and equipment while taking the drug. Above is an article about the use of Psycholanz-10 drug. Drugs with neuroleptic and antipsychotic effects are used as prescribed by a specialist. To use the drug safely and effectively, avoid unwanted side effects, and answer your questions, you need to consult a doctor, specialized medical staff for advice.
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