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Fludalt Duo is commonly used to control and prevent symptoms (wheezing and shortness of breath) caused by respiratory disease. So how is Fludalt Duo used? The following article will help readers answer these questions.
1. What is Fludalt Duo 250mcg/50mcg?
Fludalt Duo 250mcg/50mcg medicine contains the main ingredients:
Fluticasone 250mcg: belongs to the group of corticosteroid drugs, works to reduce irritation and swelling of the respiratory tract. Salmeterol 50mcg: A long-acting beta-agonist that works by relaxing the airways in the lungs to make it easier to breathe. The drug is packaged in the form of a capsule containing a powder for inhalation.
2. Uses of Fludalt Duo 250mcg/50mcg
Prophylactic treatment of asthma in cases: The patient cannot maintain efficacy on inhaled corticosteroids and long-acting beta-2 agonists or is adequately controlled with both inhaled corticosteroids and long-acting beta-2 agonists. Symptomatic treatment of chronic obstructive pulmonary disease (COPD) in COPD patients with an FEV1 <60% of theoretical (pre-bronchiectasis), a history of repeated relapses, and significant symptoms despite treatment with bronchodilators. regular bronchodilator. Contraindicated to use the drug in case:
Patients are allergic to any component of the drug Fludalt Duo. Hypersensitivity to milk proteins, treatment of asthmatic conditions or exacerbations of bronchial asthma, COPD when intensive treatment is required.
3. Dosage and usage
3.1. Dosage To be on the safe side, doctors usually prescribe the lowest dose that can effectively control symptoms. Different dosages are recommended for each condition:
Asthma:
Adults and children over 12 years old: use a combination dose of Salmeteron + Fluticasone with a strength of 50mcg/250mcg or 50mcg/500mcg, respectively. 2 times/day. If symptoms are controlled, can be reduced to 1 time/day, should be used in the evening (if nocturnal symptoms) or in the morning (if daytime symptoms) to maintain control disease status or can try costicosteroid therapy alone at the next stage. Children from 4 to 12 years old: use a combination dose of Salmeteron + Fluticasone with a concentration of 50mcg/100mcg, 2 times a day, Children under 4 years old: Do not use Salmeteron + Fluticason COPD: In adults, use the same dose. 50mcg/500mcg x 2 times/day.
Special cases : No dose adjustment is required in the elderly or in patients with renal impairment . There are no data available on the use of Fludalt Duo in patients with hepatic impairment.
3.2. How to use Fludalt Duo is for inhalation use only. Patients should be advised to take their medication daily for optimal efficacy, even in the absence of symptoms, and should be reassessed by their physician regularly to ensure that the dose of Fludalt Duo 250mcg being administered is correct. optimal for the patient.
4. Side effects
Common undesirable effects when using Fludalt Duo 250mcg include:
Candidiasis in the mouth and throat, hoarseness. Patients should rinse their mouth with water after taking the medicine to reduce this side effect. A topical antifungal may be used while taking Fludalt Duo. Tremor, palpitations, and headache are usually transient and subside with regular administration. Pneumonia (in patients with COPD), bronchitis, hypokalemia, nasopharyngitis. Joint pain, muscle pain, cramps.
5. Drug interactions
Potassium-sparing diuretics: Reduces electrocardiogram and/or hypokalemia. Beta adrenergic blocking agents: May reduce or neutralize the effect of salmeterol or produce additive effects. Monmine oxidase inhibitors (MAOIs) and tricyclic antidepressants: Consider the combination of these drugs with Fludalt Duo, or discontinue these agents for 2 weeks because salmeterl's systemic activity may be increased. Ritonavir: There is a risk of increased systemic corticosteroid effects including Cushing's syndrome and adrenal suppression. Strong Cytochrome P450 3A4 Inhibitor: Increases systemic corticosteroid effects and increases cardiovascular side effects.
6. Notes and preservation
Patients with active or latent pulmonary and fungal tuberculosis, viral or other respiratory tract infections, serious cardiovascular disorders, irregular heartbeats, thyrotoxicosis, untreated hypokalemia, have low serum potassium, have or have a history of diabetes with tolerance to certain sugars. Do not stop taking the medicine on your own or suddenly reduce the dose without consulting your doctor. Do not use Fludalt Duo for the initial treatment of mild or acute bronchial asthma. Discontinue use immediately if paradoxical bronchospasm occurs with increased wheezing and dyspnea following administration. Long-term use of high doses can cause systemic effects. Due to the side effects of headache, tremor...so be careful when using the drug for drivers or operating machinery. Pregnancy and breast-feeding: Not recommended for use in women during the above period, weighing the benefits and risks to the mother and fetus to use Fludalt Duo.
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