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Escivex 20 is a drug used in the treatment of anxiety and depressive disorders with the main ingredient Escitalopram. This is a drug manufactured by Akum Drugs & Pharmaceuticals Ltd in India. Refer to the article below to answer the question: "What does Escivex do?"
1. What are the effects of Escivex?
The active ingredient Escitalopram in Escivex is an antidepressant with a selective serotonin reuptake inhibitor mechanism (also known as SSRIs). Escivex is used to treat depression caused by mood disorders. The antidepressant, excitatory, and compulsive effects of Escitalopram are thought to be related to the inhibition of CNS Serotonin reuptake. In vitro studies have shown that Escitalopram in Escivex strongly and selectively inhibits serotonin reuptake, while the inhibitory effect on Norepinephrine and Dopamine reuptake is very weak.At the same time, Escitalopram has no appreciable affinity for other receptors such as Adrenergic (including alpha-1, alpha-2, beta), Cholinergic, GABA, Dopaminergic, Histaminergic or Benzodiazepine. The antagonistic effect with the above receptors is hypothesized to be related to many different effects, including anticholinergic, sedative and cardiovascular effects... of many other psychotropic drugs.
2. Indications and contraindications of Escivex
Escivex products are mainly indicated in the treatment of anxiety disorders and depression.
However, there are some cases where Escivex should not be used (or contraindicated), including:
Allergy to Escitalopram or any ingredients in the preparation; Concomitant use of Escivex with monoamine oxidase inhibitors (MAOIs) is contraindicated.
3. Dosage of the drug Escivex
The recommended dose of Escivex for adults with a diagnosis of generalized anxiety disorder or depression is as follows:
Initial dose: 10mg (1⁄2 Escivex 20 tablets) taken once daily, with may be increased to 20mg (1 Escivex 20 tablet) if necessary after at least 1 week of treatment; Maintenance dose: 10 to 20mg (1⁄2 to 1 Escivex 20 tablet) orally once daily; The maximum recommended dose is 20mg (1 Escivex 20 tablet) orally once a day. Recommended dose of Escivex for older adults with depression: The recommended dose is 10mg (1⁄2 Escivex 20 tablets) orally once a day.
Dosage of Escivex for children 12 to 17 years old:
Initial dose: 10mg (1⁄2 Escivex 20 tablets) orally once a day and increase to 20mg if necessary after at least 3 weeks of treatment; Maintenance dose: 10 to 20 mg orally once a day; Maximum dose: 20mg (1 Escivex 20 tablet) orally once a day.
4. Side effects of the drug Escivex
Sleepy; Dizzy ; mild nausea, belching, heartburn; Stomach upset; Constipation; Weight change; Decreased libido, lack of force or difficulty achieving orgasm; Dry mouth ; Long yawns; Tinnitus.
5. Some notes when using Escivex
Before using Escivex, patients should inform their doctor and pharmacist of the following:
History of previous allergy to Escitalopram, Citalopram or any other drugs; Currently or within the previous 14 days taking Pimozide or active Monoamine Oxidase (MAO) inhibitors such as Isocarboxazid, Phenelzine, Selegiline and Tranylcypromine; Are taking or plan to take any medications, vitamin supplements or any other supplements. Especially anticoagulants such as Warfarin, Aspirin and non-steroidal anti-inflammatory drugs (such as Ibuprofen, Naproxen), Carbamazepine, Cimetidine, Ketoconazole, Lithium, Linezolid antibiotics, medicines for anxiety, nervous disorders or anti-anxiety epileptic; are taking migraine medicines such as Almotriptan, Eletriptan, Frovatriptan, Naratriptan, Rizatriptan, Sumatriptan and Zolmitriptan; Are taking Metoprolol, other antidepressants such as Desipramine, Sedatives, Sibutramine, sleeping pills, tramadol, methylene blue, and tranquilizers. Your doctor may need to change the dose of Escivex or watch for side effects. In addition, escitalopram can cause drowsiness, so people taking Escivex should not drive or operate machinery until they are sure whether Escivex will cause drowsiness. Alcohol can also increase the drowsiness caused by Escivex.
Objects to note before taking Escivex are: the elderly, pregnant women, lactating women, children < 15 years old, people with liver failure, kidney failure, allergic hypersensitivity to any substance in the composition of the drug Escivex or patients with myasthenia gravis, hepatic coma, stomach ulcers...
6. Drug interactions of the drug Escivex
Escivex may interact with any of the following drugs;
Buspirone; Lithium; Tryptophan (L-tryptophan); Anticoagulants such as warfarin ; Migraine medications such as Sumatriptan, Rizatriptan; narcotic pain relievers such as Fentanyl or Tramadol;
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