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Combunox contains 2 main ingredients Oxycodone and Ibuprofen. The drug is indicated for short-term use to relieve severe pain. Let's learn more about Combunox through the article below.1. What does Combunox do?
Combunox is a combination of 2 main ingredients Oxycodone and Ibuprofen. Oxycodone is an opioid pain reliever. Ibuprofen is a drug in the group of non-steroidal anti-inflammatory drugs (NSAIDs). This medicine works to relieve pain, fever, and inflammation. Combunox is used short-term to relieve severe pain. Note Combunox is not for the treatment of pain caused by arthritis.
2. Dosage and usage of Combunox
Usage:
Patients need to use Combunox exactly as prescribed by the doctor. Do not use Combunox in larger amounts or for longer than prescribed. Because of the risks of addiction and drug abuse, the lowest effective dose for the shortest duration appropriate to the individual patient's treatment goals should be used. Closely monitor patients for respiratory failure during the first 24 to 72 hours of initiating treatment and after increasing the dose. Dosage:
Usual Adult Combunox Dose for Pain: The starting dose is 1 Oxycodone 5mg/Ibuprofen 400mg tablet every 6 hours as needed for pain relief, up to a maximum of 4 tablets in 24 hours. Duration of treatment with Combunox should not exceed 7 days The usual dose of Combunox for children to relieve pain: For children 14 years of age and older, the starting dose should be 1 Oxycodone 5mg/Ibuprofen 400mg tablet, taken every 6 hours as needed to pain relief. The maximum dose is 4 tablets in 24 hours and the duration of Combunox treatment should not exceed 7 days
3. Combunox side effects
Common side effects of Combunox may include: Dizziness, drowsiness, blurred vision or nausea, vomiting, abdominal pain, constipation, diarrhea. Serious side effects may occur more often in older adults and people who are malnourished or debilitated. Get medical help right away if you have signs of an allergic reaction to Combunox (rash, trouble breathing, swelling in your face or throat) or a serious skin reaction (fever, sore throat, burning in your eyes, skin pain, a red or purple rash that spreads and causes blistering and peeling). The oxycodone in Combunox can slow or stop breathing and possibly death. Call the doctor at once if the patient has difficulty breathing, shallow breathing, stops breathing during sleep, swelling or rapid weight gain, skin rash of any size, pale skin; signs of stomach bleeding such as bloody stools, coughing up blood, or vomit that looks like coffee grounds; kidney problems such as urinating little or no, swelling feet or ankles, feeling tired or short of breath; liver problems such as loss of appetite, diarrhea, upper stomach pain, fatigue, flu-like symptoms, dark urine, jaundice; high levels of serotonin in the body such as agitation, hallucinations, fever, sweating, fast heart rate, muscle stiffness, convulsions, loss of coordination, vomiting.
4. What are the precautions when using Combunox?
Fatal side effects can occur if a patient takes Combunox with alcohol or with other drugs that cause drowsiness or slow breathing. Patients should not use Combunox if they are allergic to Oxycodone or Ibuprofen, have severe asthma or breathing problems, have a blockage in the stomach or intestines. Ibuprofen may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with time of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at higher risk. Combunox is contraindicated for the treatment of pain immediately before and after coronary artery bypass graft (CABG) surgery. Ibuprofen may increase the risk of serious gastrointestinal side effects including bleeding, ulceration, and perforation of the stomach. stomach or intestines, which can be fatal. These events can occur at any time during use and are asymptomatic. Elderly patients are at increased risk for serious gastrointestinal events. Pregnant women: If you are pregnant, you should not take Combunox unless your doctor tells you to. Taking NSAIDs during the last 20 weeks of pregnancy can cause serious problems for the unborn baby and possible complications with the pregnancy. If a patient takes opioid medication while pregnant, the child may become dependent on the drug. This can lead to life-threatening withdrawal symptoms in the baby after birth. Lactation: Consult your doctor before using Combunox while breastfeeding. Contact your doctor if you notice that your child is severely drowsy or breathing slowly. Overdose: An opioid overdose can be fatal, especially in children or others using the drug without a prescription. Overdose symptoms may include black or bloody stools, coughing up blood, severe drowsiness, slow or no breathing. Your doctor may prescribe Naloxone (a medicine to reverse the effects of opioids).
5. Drug interactions
Drug interactions that will affect treatment results and/or increase side effects. Opioids can interact with many other drugs and cause dangerous side effects or death. Inform your doctor if you are taking cold or allergy medicine, asthma/COPD medication, diuretics, motion sickness medicine, irritable bowel syndrome or overactive bladder medication, medication that causes an overactive bladder. anesthetics, prescription opioid or cough medicine, sedatives such as Diazepam, Lorazepam. Combunox should not be used with medications that slow breathing, such as sleeping pills, muscle relaxers, drugs for mood disorders or mental illness. Medications that affect serotonin levels in the body, such as those for depression, Parkinson's disease, and migraines, can increase the side effects of Combunox. The article has provided an overview of the drug Combunox. This is a pain reliever and potentially addictive, patients are not allowed to self-medicate but need to visit medical facilities for appropriate indications.
