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Gemtuzumab Ozogamicin is a prescription drug, an antibody drug conjugate, used in the treatment of cancer. Find out more information about the drug through the article below.
1. What is MylotargTM?
MylotargTM brand-name drug with the main ingredient is Gemtuzumab Ozogamicin, which is prepared in the form of an intravenous solution.
Monoclonal antibodies are created in the laboratory to attach to targets found on specific types of cancer cells. The antibody "calls" the immune system to attack the cell it is attached to, resulting in the immune system killing the cell. These antibodies can work in a variety of ways, including stimulating the immune system to kill cells, stop cell growth, or other functions necessary for cell growth. ...
This drug is an anti-CD33 monoclonal antibody that, in combination with calicheamicin and a drug binder, binds the antibody fraction to the target cells. The purpose is to allow entry, damage the DNA of cancer cells and destroy them.
2. Uses of the drug MylotargTM
Mylotarg is used in the treatment of a certain type (CD33 positive) of newly diagnosed acute myeloid leukemia in adults and children who are at least 1 month old.
Mylotarg is also treated for CD33-positive acute myeloid leukemia after other treatments have failed or have been discontinued in adults and children at least 2 years of age.
3. Usage and dosage of MylotargTM
How to use: The drug is given by intravenous (IV) line, can be used alone or in combination with other drugs
Dosage: Depending on your condition, height, weight that the doctor will give determine the appropriate dose and duration of each course of treatment. Before each dose, you will be given acetaminophen, diphenhydramine, and possibly corticosteroids, to prevent possible adverse reactions.
4. Possible side effects when taking MylotargTM
Common or important MylotargTM side effects may include: yellowing of the skin or eyes, dark, brown urine, or abdominal pain because you may be having symptoms of liver toxicity. In addition, the patient may have thrombocytopenia, vomiting, constipation, infusion reaction, fatigue, anemia... at this time, the patient should call the doctor to consult about the current condition.
5. Things to note when taking Mylotarg
Before taking you need to inform your doctor about a history of allergy to any ingredient of the drug or any antigens, history of liver disease, liver disease; long QT syndrome, stem cell transplant; or electrolyte imbalance...
The above medical conditions may not be safe if you take them, so talk to your doctor to weigh the benefits and risks before taking them.
Exposure of the fetus to this drug can cause birth defects, so pregnancy is not recommended during this time. Effective contraception is required during treatment and for at least 6 months after treatment for women and 3 months for men. You should not breast-feed while you are taking this medicine or for one month after your last dose.
Above is some information about the use of Mylotarg, if you have any questions, you should consult your doctor or pharmacist before using the drug.
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Reference source: oncolink.org
