Can more than one diuretic be combined to increase the effect?

Question
Hello doctor, my question is as follows: Can we use a combination of loop diuretics with other diuretics to increase the effect? Please advise me doctor.
Anonymous customer question
Answer
Hello, this question will be answered by the doctor as follows:
Currently, there are many groups of diuretics used, each group has its own mechanism and effectiveness. different so can be used in combination in treatment. Loop diuretics as you mentioned work at the loop of henle of the glomerulus, have diuretic effects and cause potassium loss, so they can be combined with other diuretics to increase the therapeutic effect and limit the side effects of diuretics. diuretics as in combination with potassium-sparing diuretics (Spironolactone).
If you need more advice, you can go to the hospitals of Vinmec Health System for more detailed answers.
Thank you for your question to Vinmec. Best regards!
Master, Doctor Tran Hong Nhat - Interventional Cardiologist - Cardiovascular Center - Vinmec Central Park International General Hospital.