Is type 2 diabetes genetic?
Diabetes is a disease that currently tends to be younger. Before this situation, many people wonder if type 2 diabetes is inherited and if so, how is diabetes inherited?
1. How is diabetes inherited?
Diabetes, also known as diabetes, has 2 types:
Type 1 diabetes: A disorder of glucose metabolism due to a lack of insulin hormone. Type 2 diabetes: Impaired function of the hormone insulin. The causes of type 1 and type 2 diabetes are different. Through the media, we know that diabetes is a genetic disease. However, the disease is not only dependent on the genetic makeup of the disease, but also on the influence of the environment.
For type 1 diabetes, the inheritance rate is calculated as follows:
If both parents have type 1 diabetes, the chance of children being born with this disease is about 30%. If only the father has diabetes, the chance of the children being born with diabetes is about 6%. If only the mother has diabetes, the chance that her children will inherit the disease is about 4%.
2. Is type 2 diabetes hereditary?
According to the American Diabetes Association, the rate of inheritance of type 2 diabetes is quite high and in most cases this is the cause of diabetes. The heritability rate for type 2 diabetes is as follows:
If a parent is diagnosed with type 2 diabetes before the age of 50, the chance of their children being born with this disease is 14%, and after the age of 50, the rate is 7.7%. If both parents have type 2 diabetes, there is a 50% greater chance that their children will inherit the disease. If only the father or mother has type 2 diabetes and is under 50 years old, the odds of having this disease inherited are 14% and 7.7% after the age of 50. Although the inheritance rate in type 2 diabetes is higher, depending on environmental factors, the above rate can change. Therefore, the advice given by doctors is to pay attention to build a healthy lifestyle to reduce the risk of affecting genes and the risk of disease.
3. Genetics linked to type 2 diabetes
Thus, statistics show that the heritability of type 2 diabetes is higher than that of type 1. Until now, studies on genetic mutations in diabetes have revealed a number of genes. Related to the ability to regulate glucose in the body, that is:
Control genes regulate the production of insulin and glucose, regulate insulin levels, control the body's sensitivity to blood glucose levels. Other genes are involved such as the Glucagon hormone and receptor that regulates glucose, the Urea Sulfonylurea receptor that regulates insulin, the Glucose transporter gene 2, the TCF7L2 gene that affects glucose production and insulin secretion, etc. , people with the above genes have a higher risk of developing type 2 diabetes, but it is important to understand clearly that carrying this gene does not mean disease. Compared with normal people, people who carry the mutated gene will have a higher risk of getting the disease.
As stated above, part of the cause of type 2 diabetes is environmental factors. If children are born in families with parents with type 2 diabetes, in addition to genetic causes, it can also be due to lifestyle including diet and exercise habits.
4. Genetic testing for type 2 diabetes
Today, with the advancement of science, it is possible to conduct genetic testing for type 2 diabetes, but the accuracy is not high because of the risk of genetic mutations. To be able to diagnose a patient with hereditary type 2 diabetes, it is necessary to combine the following factors:
People with high blood pressure A family history of type 2 diabetes Body mass index ( BMI) History of gestational diabetes Tests show increased levels of cholesterol and triglycerides In fact, genetic testing and screening for type 2 diabetes is still very difficult because it is not possible to accurately assess the impact of diabetes. The two factors that develop the disease are genetics and the external environment. This also means that we can reduce the risk of disease progression by changing our lifestyle and daily activities.
Specifically, maintaining a healthy weight or losing weight, a reasonable and healthy diet, and regular physical activity will help maintain the blood sugar index, thereby delaying it. or prevent type 2 diabetes.
5. How can hereditary diabetes be prevented?
A healthy lifestyle can help improve and prevent hereditary diabetes, specifically:
Regular exercise, sports, increase physical activity, at least 30 minutes per day day. Limit eating foods high in starch, sugar, and fat. Each meal should consume more fruits, vegetables, foods rich in fiber. Avoid or limit, give up the habit of using regular stimulants such as drinking alcohol, smoking, ... Try to maintain a moderate weight, within the allowable threshold, avoid obesity. . Try not to get stressed. Memorize the schedule of health check-ups or regular check-ups to promptly detect and treat diseases. Type 2 diabetes is hereditary and has a higher rate of heritability than type 1 diabetes. However, it is possible to limit intergenerational rates and prevent progression by developing a healthy and reasonable lifestyle.
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