Uses of Acapellas

Acapellas contains the active ingredient Simethicone, which is indicated in the treatment of symptoms of bloating and flatulence. Let's learn about the uses and notes when using Acapellas through the article below.

1. Uses of the drug Acapellas

1.1. Point

Acapellas medicine containing the active ingredient Simethicone 30mg is indicated in the treatment of symptoms of bloating and flatulence. In some cases, Acapellas can be used in the treatment of some gastrointestinal diseases.

1.2. Pharmacodynamic

Active ingredient Simethicone is a mixture of silicon dioxide and polydimethylsiloxane with anti-foaming effect. Simethicone has the effect of reducing the surface tension of air bubbles, breaking the air bubbles or agglomerating them and expelling them, so that the drug has an anti-flatulence effect. Therefore, Simethicone is used to relieve symptoms when too much gas accumulates in the gastrointestinal tract caused in both children and adults, such as swallowing gas in the stomach, gas produced due to digestion. of food that is not digested by intestinal bacteria.
Simethicone has been shown to be effective against Helicobacter pylori . The minimum inhibitory concentration of simethicone for H.pylori ranges from 64 to 128 mg/liter.

1.3. Pharmacokinetics

After oral administration, Simethicone is not absorbed from the gastrointestinal tract and does not interfere with gastric acid secretion or absorption of nutrients. The drug is physiologically inert. Simethicone is eliminated in the feces unchanged.

2. Dosage of Acapellas

Simethicone is available in capsule, tablet, liquid form and is taken orally. Chewable tablets need to be chewed thoroughly before swallowing, should be taken before eating to ensure maximum effectiveness.
Dosage of Acapellas depends on the condition of the bottle, the recommended dose is 4 times / day and do not take more than 6 Simethicone tablets or 8 capsules per day (unless prescribed by the treating doctor). The liquid form can be mixed with powdered milk or 30ml of cooled boiled water when used in infants.
In case the patient needs to prepare for X-ray, it is necessary to take medicine 2 or 3 days before the scan.

3. Side effects of Acapellas

Some side effects may be encountered when using Acapellas as follows:
On the gastrointestinal tract: Diarrhea, nausea, abdominal pain; On the skin: Allergic reactions, rash ; Body as a whole: Headache, dizziness. In case of experiencing side effects, the patient should stop using the drug and immediately notify the doctor or go to a medical facility for timely treatment.

4. Notes when using Acapellas

4.1. Contraindications

The use of Acapellas is contraindicated in the following cases:
Patients are sensitive to any component of the drug; Patients with bowel obstruction or perforation (suspected or diagnosed); Patients with renal failure, pregnant women and lactating women.

4.2. Use caution

Acapellas should be used with caution in children for the treatment of colic because there is not enough information on the benefits and safety for this age group. Do not use the drug in excess of the recommended dose (more than 12 tablets / day unless directed by the treating doctor). Avoid drinking carbonated beverages (soft drinks, soda) or foods that increase the amount of gas in the stomach. Pregnancy: There are no studies demonstrating the ability of Simethicone to cross the placenta, however, the drug's intestinal absorption is limited, which reduces the possibility of exposure to the fetus. Lactation: There have been no reports of risk in lactating women, nor a measurement of the amount excreted in breast milk. Therefore, it is necessary to weigh the benefits and risks when using this drug in this population.

5. Drug interactions

Simultaneous use of Simethicone and levothyroxine reduces the absorption of levothyroxine, thereby reducing the effectiveness of levothyroxine, hypothyroidism. If it is necessary to use these two drugs, they must be taken at least 4 hours apart. Monitor TSH levels and other assessments of thyroid function at the initiation and discontinuation of Simethicone during levothyroxine therapy.

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