Precautions when using Cefotiam 0.5g

Cefotiam 0.5g has the main ingredient Cefotiam belongs to the group of drugs that treat parasites, infections, fungi and viruses. It is used to treat blood infections, bronchitis, and lung infections.

The doctor prescribes the use of drugs to treat the following cases:
Blood infections; Cholecystitis ; Nephritis, cystitis, urethritis , prostatitis; Meningitis, otitis media; Tonsillitis, pneumonia, bronchitis, patients with lung infections; Spondylitis, septic arthritis; Preoperative wound, burn wound infection, subcutaneous abscess, toxic boil under the skin due to bacterial infection, pus production, nail boil; Peritoneal infection, intrauterine infection, pelvic inflammatory disease, tendonitis, peritonitis, pyelonephritis, cystitis, urethritis. Do not use the drug for the following cases:
People with a history of shock reactions to Cefotiam ingredients. The patient has a history of allergy to beta-lactam antibiotics.

How to use Cefotiam 0.5g:
Infusion: Use immediately after preparation and dissolve it with Bifotirin injection in distilled water for injection, 5% glucose solution and isotonic sodium chloride solution Intravenous: Dissolve Dissolve the dose of 0.25 - 2g into the solution for infusion such as glucose, amino acids, electrolytes and the infusion time lasts from 30 minutes to 1 hour, when dissolved, it is not necessary to use distilled water for injection. Dosage is adjusted according to age and severity of the disease. Reference dose is as follows:
Adults:
Use for intravenous injection with a dose of 0.5 - 2g/day, divided into 2-4 times a day; For patients used to treat blood infections can be up to 4g / day; In patients with renal impairment, the dose should be adjusted depending on the creatinine clearance. Specifically: Creatinine clearance >=16.6ml/min can be used in the same dosage regimen as patients with normal renal function. With creatinine clearance <16.6 ml/min, dose reduction to 75% of that used in patients with normal renal function is required with dosing intervals every 6 or 8 hours. For children:
Use for intravenous injection with a dose of 40-80mg/kg body weight/day divided into 3-4 times; The dose for the treatment of severe or persistent infections such as bacteremia and meningitis may be increased to 160 mg/kg/day.

Some side effects should be noted when using the drug such as:
Shock reactions may occur and if this sign occurs, the patient should stop using the drug immediately; Hypersensitivity to the ingredients of the drug causes reactions such as rash, urticaria, skin redness, itching or fever. More seriously there is toxic necrosis of the skin and Steven - Johnson syndrome, but this case is less common; Blood: Thrombocytopenia, eosinophilia, anemia, agranulocytosis; Kidney: Periodic monitoring of renal function should be planned because Cefotiam 0.5g makes kidney disease worse; Gastrointestinal: Abdominal pain and diarrhea, loss of appetite, nausea/vomiting. Some rare cases lead to serious intestinal conjunctivitis such as pseudomembranous colitis, which is evident in bloody stools, if this condition occurs, the drug should be discontinued; Vitamin deficiency: The patient may have a vitamin K deficiency, which causes the blood to not clot and tend to bleed, or a lack of B vitamins, which can lead to glossitis, anorexia or neuritis, but the This side effect is also rare; Respiratory: A rare reaction, PIE syndrome with fever, cough, dyspnea, abnormal X-ray results, or eosinophilia occurs. If any of the above symptoms occur, the drug should be discontinued immediately and appropriate treatment instituted, such as administration of adrenal hormones; Some other side effects such as: stomatitis or candida, headache, dizziness.

Do not use the drug for patients with a history of hypersensitivity to Cefotiam or any antibiotic of the Cefalosporine and Penicillins group; Do not use or use the drug with caution in patients with severe renal impairment; Be careful with patients or their relatives with allergies such as asthma, bronchi, rash or urticaria; The drug should be used with caution in patients with malnutrition problems or in a debilitated state. Because they may have a side effect of vitamin K or vitamin B deficiency; Patients should periodically check liver function, kidney function, hematology during the treatment period; For pregnant women only really use when necessary, weigh the benefits and harms that the drug brings because there are no clinical studies to prove it is really safe for pregnant women; When used in combination with antibiotics of the Cephalosporin family, the diuretic Furosemide can cause nephrotoxicity. The article has provided information about uses, doses and precautions when using Cefotiam 0.5g. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Cefotiam 0.5g exactly as directed by your doctor.