Econtra drug: Uses, indications and notes when using

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Econtra EZ is also known as Levonorgestrel. Birth control pills suitable for family planning. Econtra belongs to the Gestagen drug category, the tablet has a maximum strength of 0.03mg. Do not use the drug during pregnancy and lactation or intend to become pregnant.

1. What is Econtra?

Econtra (Levonorgestrel) is a synthetic progestogen derived from nortestosterone. The main ingredient in Econtra is Microval, Norgeston.The drug is used in case of emergency contraception and should not be used regularly for contraception of family planning.

2. Mechanism of action

The active hormone progesterone prevents the release of an egg (ovulation) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching the egg for fertilization and changes the lining of the uterus to prevent a fertilized egg from attaching.
Pharmacokinetics
Absorption: After oral administration of Econtra, the drug is rapidly and completely absorbed from the gastrointestinal tract and does not undergo first-pass metabolism in the liver. The bioavailability of Econtra is almost 100%. Distribution: After entering the body, the drug is distributed in serum, and levonorgestrel binds to sex hormone-binding globulin (SHBG) and to albumin. Metabolism: Levonorgestrel is metabolized in the body by deoxygenation, followed by conjugation. Elimination: The rate of clearance of the drug may vary several times between individuals; half-life is 13 hours. Levonorgestrel and its metabolites are excreted in feces and urine. A serum levonorgestrel concentration of 0.2 mg/l may inhibit ovulation. After entering the body, peak serum concentrations occur after 30 minutes to 1 hour. Oral administration of 30 mg of Econtra has a peak concentration of 0.7-0.9 mg/liter.

3. How to use Econtra

Take 1 pill by mouth with or without food as soon as possible after unprotected sex. It is best taken within 72 hours (3 days) of unprotected sex.
If you vomit within 2 hours of taking this medicine, tell your doctor to ask if you need to take another dose.
While you are taking this medicine, your menstrual cycle and the amount of bleeding you have may change. It is possible that your first period will be delayed or earlier than your normal period. No need to worry tell your doctor right away for better understanding. You can also take a pregnancy test to make sure you're not pregnant after taking the pill.

4. Side effects

Some Common Adverse Reactions (ADRs): Irregular periods are common in users of the single progestogen oral contraceptive and are often a reason for users to change methods.
Common, ADR > 1/100:
Neurological: Headache, depression, dizziness, fatigue. Endocrine: Edema, breast pain, breast tenderness. Gastrointestinal: Nausea, vomiting, abdominal pain Urinary - genitourinary: There may be cases of frequent or prolonged bleeding or little bleeding, amenorrhea. Uncommon, 1/1000 < ADR < 1/a100:
Whole body: Change in weight. Nervous: Decreased libido. Endocrine: Hirsutism, sweating, baldness.

5. Precautions

Before taking Econtra, tell your doctor or pharmacist if you are allergic to Microval, Norgeton ; or another progestin (such as norethindrone); or if you have any allergies to other products.
If you have a medical history, especially: unexplained vaginal bleeding, caution should be exercised when using the drug, it is best to consult a specialist.
This drug is contraindicated for women during pregnancy. If you are pregnant or suspect that you are pregnant, check your body condition before taking the medicine to avoid an accident.

6. Econtra . interaction

Econtra if taken with drugs that induce liver enzymes such as barbiturates, primidone, phenobarbital, phenytoin, phenylbutazone, rifampicin, carbamazepine and griseofulvin may reduce the contraceptive effectiveness of the drug. Women who are taking long-term liver enzyme inducers must use a different method of contraception or use a different medication.

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Reference source: webmd.com