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Question
Hello doctor,
What does the map-shaped skull X-ray result mean? Is it dangerous? Thanks for the advice doctor.
Anonymous customer
Answer
Answered by Doctor Ton Nu Tra My - Department of Diagnostic Imaging, Vinmec Central Park International General Hospital.
Hi,
With the question “What does the map-shaped skull X-ray result mean? ”, the doctor answered as follows:
Map skull defect is a descriptive term in bone imaging. Usually this image is seen in Langerhans histiocytosis (English name is Langerhans cell histiocytosis or other names are eosinophilic granuloma, Hand-Schüller-Christian disease). Langerhans cells are white blood cells in the normal immune system that play an important role in defending the body against viruses, bacteria, and other invaders. In patients with LCH syndrome, Langerhans cells multiply abnormally. Instead of a protective effect on the body, these cells overgrow causing damage to the hematopoietic system, bone tissue, liver, spleen, skin, lung...
Langerhans cell histiocytosis can manifest in Multiple organs:
Bone lesions: may be swelling on the skin of the affected bone, bone pain, X-ray shows bone resorption, atlas bone defect without periosteal reaction May have protrusion, or inflammation Middle ear Skin lesions: common are purpura papules (lesions are diffuse papules such as seborrheic eczema, accompanied by petechiae and purpura) Lesions of the hematopoietic system: anemia, leukopenia, platelets Liver damage: Enlarged liver, liver dysfunction Enlarged spleen Enlarged lymph nodes Lung damage: Cough, difficulty breathing may occur. Chest radiograph shows diffuse nodular infiltrates, or diffuse pulmonary fibrosis resembling millet tuberculosis. diabetes insipidus. The diagnosis requires evaluation by a hematologist and confirmation of the diagnosis by biopsy of the lesion for histopathological examination.
If you still have questions about the map-shaped skull X-ray results, you can go to a medical facility under Vinmec Health System for early examination and treatment. Thank you for trusting and sending questions to Vinmec. Wishing you lots of health.
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