Cyclical vomiting syndrome (CVS) in adults is a disorder characterized by sudden recurrent episodes of nausea, vomiting, and abdominal pain, separated by different periods of normal health. The aim of this paper is to further characterize the clinical presentation and propose new diagnostic criteria for cyclic vomiting syndrome in the adult population.

Cyclical vomiting syndrome (CVS) in adults is a disorder characterized by sudden recurrent episodes of nausea, vomiting, and abdominal pain, separated by different periods of normal health.

Alternating presentation of disease and disease-free phase distinguishes cyclic vomiting syndrome (CVS) from other nausea and vomiting disorders. This pathology is increasingly recognized in adults and leads to significant morbidity and poor quality of life. Recent referral models suggest prevalence up to 0.2% in the adult population and an explanation for nausea and vomiting in 12% of the referral population to a teaching academic center . In this article, we discuss the diagnostic criteria of this pathology

Alternating patterns of disease and disease-free periods help distinguish cyclic vomiting syndrome (CVS) from other nausea and vomiting disorders. This pathology is increasingly recognized in adults and leads to significant morbidity and poor quality of life.