Peripheral vascular disease includes systemic arterial and venous disease distal to the heart. The disease mainly occurs in the extremities, although the disease is not life-threatening, if not treated early, it can leave serious consequences such as limb ulcers, even amputation due to insufficient blood supply leading to necrosis. death.

Raynaud's syndrome is at risk of recurrence when the patient is exposed to cold water, leading to peripheral vasoconstriction. Raynaud's can be a symptom of many different diseases, if not treated promptly, it will affect the patient's daily life.