Preeclampsia is one of the obstetric complications that cause serious consequences for the mother and fetus. In order to minimize the negative effects of preeclampsia, scientists have found that changes in the concentration of pluripotent factor (PlGF) and anti-angiogenic factor (sFlt-1) occur quite early before the symptoms of preeclampsia appear. Therefore, it is possible to quantify pluripotent factor for early diagnosis of preeclampsia.