The main underlying mechanisms of noncardiac chest pain include gastroesophageal reflux, esophageal dysfunction, and esophageal hypersensitivity. Gastroesophageal reflux disease may be the most common cause of noncardiac chest pain.

The main underlying mechanisms of noncardiac chest pain include gastroesophageal reflux, esophageal dysfunction, and esophageal hypersensitivity. Gastroesophageal reflux disease may be the most common cause of noncardiac chest pain.

Chest pain is a feeling that many people often experience, which can be caused by many reasons. In order to make an accurate diagnosis of noncardiac chest pain, a number of tests and physical examination by a specialist are required.

Gastroesophageal reflux disease (GERD) is a common gastrointestinal (GI) disease with worldwide prevalence and high prevalence in Western countries.

Non-cardiac chest pain is a common disorder that affects the patient's life and work. However, despite its chronic nature, non-cardiac chest pain does not affect the patient's mortality rate.

The esophagus functions to carry food from the mouth to the stomach, where digestion begins. Efficient esophageal transit requires a coordinated, sequential pattern of peristaltic movements to push food down from above and clear refluxed acid and bile from below. Disruption of this highly coordinated muscular movement is called esophageal dysmotility.

Many patients with prolonged chest pain, when they go to the cardiologist, are diagnosed with cardiac neurosis or have no obvious disease but the disease still does not improve. When they see a gastroenterologist, the patient is found to have reflux esophagitis and the doctor concludes that the patient's chest pain is caused by gastroesophageal reflux.

Noncardiac chest pain is defined as recurrent chest pain that is indistinguishable from ischemic heart disease after exclusion of a cardiac cause. Noncardiac chest pain is a common disorder that results in significant health care utilization and work absence. However, despite its chronic nature, noncardiac chest pain does not affect patient mortality.

Gastroesophageal reflux disease (GERD) is the most common cause of noncardiac chest pain. Also known as acid reflux, it causes 22 to 66 percent of noncardiac chest pain episodes. Other, less common esophageal problems that can cause chest pain include muscle problems, also known as esophageal dysmotility.