Maternal and fetal blood group incompatibility can cause hemolytic anemia, leading to jaundice in the newborn. Maternal and fetal blood group incompatibility includes ABO blood group incompatibility and Rh incompatibility.

Maternal-fetal blood group incompatibility is a phenomenon in which the fetus's blood is incompatible with the mother's blood group, causing hemolytic anemia and jaundice in the newborn. There are two common types of blood group incompatibility: ABO blood group incompatibility and Rh blood group incompatibility.

When you're trying to become a mother, one of the tests you'll have is a prenatal antibody screen. This prenatal test looks for antibodies in your body, a special protein in your blood that's made by your immune system.

The Rh blood group system is one of the most important blood group systems for humans, along with the ABO system. However, in Vietnam, 99.96% of people belong to the Rh+ blood group and only 0.04-0.07% of people belong to the Rh-negative blood group. Therefore, people with Rh-negative blood group are rare and need to be careful in blood transfusion and obstetrics.