Metabolic syndrome refers to a group of cardiovascular risk factors whose underlying causes are related to insulin resistance. This syndrome includes obesity, hypertension, hyperglycemia, and elevated blood triglycerides.

Metabolic syndrome is defined as a cluster of cardiometabolic risk factors associated with insulin resistance. In addition to the importance of each individual risk factor, the combination of abdominal obesity, impaired glucose metabolism, dyslipidemia, and hypertension collectively known as the metabolic syndrome, individuals with these conditions have a markedly increased risk of type 2 diabetes and cardiovascular disease.

Menopause is the stage that marks the end of fertility, which has been gradually declining over time. The transition from perimenopause to menopause is associated with the emergence of many features of the metabolic syndrome, which are either a direct consequence of ovarian failure or an indirect consequence of the redistribution of body fat in response to estrogen deficiency.